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15 labs · 1 student voices
Other departments in Faculty of Science and Technology ›Faculties at Tokyo University of Science ›
Ryuichi Nishihama, Professor
1 student voices
The Nishihama Lab studies the mechanisms of growth and development shared by land plants. Because plants use the products of photosynthesis for their own growth, they have evolved ways of regulating growth that make good use of photosynthesis. Land plants evolved from a single common ancestor, so they share a set of genes and the mechanisms that regulate their functions. Mainly using the liverwort Marchantia polymorpha, a bryophyte and a model organism, the lab uses genetic modification techniques and omics analysis to uncover how growth is regulated in coordination with photosynthesis.
Masahiro Nakajima, Associate Professor
0 student voices
The Nakajima Lab studies enzymes that act on glycans, using β-1,2-glucan, a unique glycan made of linked glucose units, as its main subject. The lab searches for enzymes that synthesize or degrade new glycans, solves their three-dimensional structures by X-ray crystallography, and investigates how the enzymes work at the atomic level. It also synthesizes new glycans with applications in mind and explores the functional properties of those glycans.
Yoshikazu Nakamura, Professor
0 student voices
The Lipid Biology (Nakamura) Lab studies the phospholipids that make up cell membranes and the enzymes that metabolize them. Through basic medical and biological research, the lab aims to produce results that can contribute to medicine. Its subjects include skin aging, organ fibrosis and the malignant progression of cancer, and skin diseases accompanied by abnormal skin barrier function. On the lab's website it is presented as the “Nakamura Lab,” and it was founded in 2019.
Koji Kuramochi, Professor
0 student voices
The Kuramochi Lab uses compounds it synthesizes itself as tools, aiming to elucidate biological phenomena at the molecular level. Within a single lab, it takes on a broad range of research spanning chemistry, biology, physics, and the boundary areas between them. Starting mainly from biologically active compounds, the lab carries out an integrated line of research, from synthesis and isolation to evaluation of activity and function, analysis of mechanism of action, and molecular design. The lab was established in April 2016.
So Maezawa, Professor
0 student voices
The Epigenome Dynamics Lab studies how germ cells such as sperm and eggs are formed, focusing on the epigenome. The epigenome is a system that controls whether genes are turned on or off, and the state of germ cells changes through its action. In addition to investigating how the epigenome is regulated and how environmental factors affect it, the lab aims to develop technologies for artificially editing the epigenome of germ cells and to apply them to reproductive medicine. Big data analysis of the epigenome and gene expression is essential to this research.
Toshiki Furuya, Professor
0 student voices
The Furuya Lab studies microorganisms and enzymes, with the aim of elucidating their functions and applying them. Microorganisms in soil and in the human gut play important roles in ecosystems and in the body, yet the functions of only a very small fraction of them are known. The lab works to discover new microorganisms and enzymes and to clarify their functions. The functions it uncovers are intended for application to the production of useful substances and to environmental remediation.
Naoyuki Wada, Professor
0 student voices
The Wada Lab studies how the skeletons of vertebrates are formed. The migration, adhesion, proliferation, and differentiation of skeleton-forming cells are precisely regulated according to the timing and location of development. Similar regulatory mechanisms are thought to operate during organ regeneration as well. The lab investigates these processes from multiple perspectives, from genes to cells, tissues, and organs, and also uses mathematical models.
Misaki Sakashita, Lecturer
0 student voices
The Sakashita Lab studies how vertebrae, the bones that make up a fish's backbone, are shaped. The lab focuses on how the alignment of collagen fibers changes in response to externally applied forces, and investigates the mechanism that determines bone shape. The lab's research keywords also include bony fishes and computer simulation.
Mahito Sadaie, Professor
0 student voices
The Sadaie Lab (Cancer Cell Biology) conducts basic biological research to find the weaknesses of cancer cells and lead to the development of methods to suppress cancer. The lab pursues two main lines of research: one targeting the mechanisms that maintain telomeres at the ends of chromosomes, and one using methods that drive cells into cellular senescence. The lab also takes an approach that drives target cells not only to death but into senescence.
Tomoko Masaike, Associate Professor
0 student voices
The lab studies how the unit structures at each level, from a single enzyme molecule up to tissues, carry out their functions. The lab records video with modified microscopes and combines it with biochemical measurements to examine the causal relationships among structural change, reaction, and function. The lab aims to apply this work to elucidating respiratory diseases and developing highly sensitive biodevices.
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