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Developmental Biology (Wada Lab)
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A lab exploring how skeletal shape is formed and regenerated, from genes to mathematical models.
AboutAbout the lab
How is skeletal shape determined, and how does it regenerate?
The Wada Lab studies how the skeletons of vertebrates are formed.
The migration, adhesion, proliferation, and differentiation of skeleton-forming cells are precisely regulated according to the timing and location of development.
Similar regulatory mechanisms are thought to operate during organ regeneration as well.
The lab investigates these processes from multiple perspectives, from genes to cells, tissues, and organs, and also uses mathematical models.
Key terms
- Morphogenesis
- Morphogenesis: the process during development by which the shape of an organism's body and organs is formed.
- Differentiation
- Differentiation: the process by which cells change into cells with different roles.
- Mathematical model
- Mathematical model: a method that expresses the mechanism of a phenomenon with equations or similar means, in order to reproduce or predict changes in shape.
ResearchResearch themes
The shape of a vertebrate is determined by the form of its skeleton, including bone and cartilage. The lab studies the mechanisms that regulate cell behavior during morphogenesis and regeneration, from multiple perspectives ranging from genes to organs, together with mathematical models.
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MembersFaculty
- ProfessorNaoyuki Wada
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Regeneration of bones” Jacques Christophe Werner (1798–1856) / Public domain (cropped)
- Mechanisms of Skeletal Shaping and Regeneration: “Scientist checks cell culture flask on microscope” Peter Saxon / CC BY-SA 4.0 (cropped)
- Related lab (がん細胞生物学
（定家 研究室） ): “Telomeres” AJC1 / CC BY-SA 4.0 (cropped) - Related lab (応用微生物学
（荒添研究室） ): “Fission yeast (Schizosaccharomyces pombe)” Database Center for Life Science (DBCLS) / CC BY 3.0 (cropped)
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