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1,294 labs · 618 student voices
Shintaro Iwasaki, Visiting Associate Professor
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The Iwasaki Lab studies how translation, the reaction in which proteins are made from RNA, is regulated. RNA was long thought to be merely a messenger carrying the information for proteins, but it has become clear that the amount and quality of protein produced from an RNA cannot be simply predicted. The lab aims to clarify which RNAs are regulated and how, and how this regulation governs life. It combines two approaches: comprehensive analysis using next-generation sequencers and classical biochemistry.
Shinya Honda, Visiting Professor
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The Honda Lab studies protein engineering and synthetic biology. Building on knowledge of biophysical chemistry, structural biology, and computational chemistry, the lab creates artificial proteins intended for medical use. The lab also works on developing foundational technologies that support the biopharmaceutical industry. Research takes place at the National Institute of Advanced Industrial Science and Technology, where students can conduct research with practical applications in mind within a national research institute.
Yukihide Tomari, Professor
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The Tomari Lab studies the functions and operating principles of non-coding RNAs, which act without being translated into proteins. Cells contain a wide variety of non-coding RNAs, including small RNAs such as miRNAs and long non-coding RNAs, which are thought to finely regulate gene activity. However, how they are produced and by what principles they work remain largely unknown. Using approaches such as in vitro reconstitution of biochemical reactions and single-molecule imaging, the lab takes on the wonders of the RNA world from three main perspectives.
Hiroyuki Seimiya, Visiting Professor
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The Seimiya Lab studies, at the molecular level, the weaknesses found only in cancer cells, and researches new anticancer drugs that target them. The research takes place in the Division of Molecular Biotherapy at the Cancer Chemotherapy Center of the Japanese Foundation for Cancer Research. The lab focuses on telomeres, which are involved in the unlimited proliferation of cancer cells, and on cancer stem cells, which are a cause of drug resistance. The lab pursues both basic research that clarifies how cancer arises and applied research that searches for compounds that inhibit the function of targets and tests how well they work.
Ryohei Katayama, Visiting Associate Professor
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The lab studies, at the molecular level, how cancer drugs stop working and how cancer metastasizes. Its research takes place in the basic research division of the Cancer Chemotherapy Center, Japanese Foundation for Cancer Research. The lab aims to discover molecules that can serve as therapeutic targets, as well as inhibitors and new treatment approaches. In collaboration with the Cancer Institute Hospital of JFCR, the lab carries out research ranging from basic science to work closer to the clinic, including the use of patient-derived specimens.
Atsuya Nishiyama, Professor
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Nishiyama Lab studies at the molecular level the mechanisms of "cell memory," in which cells maintain their own state and pass it on even after they divide. The cells of the body carry nearly identical DNA, yet neurons remain neurons and hepatocytes remain hepatocytes, each keeping its own characteristics. What determines those characteristics is epigenomic information written on DNA and histones. In particular, the lab focuses on how DNA methylation is inherited as DNA is replicated.
Naohiro Noda, Visiting Professor
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The Noda Lab studies the development and application of new technologies for analyzing biomolecules such as nucleic acids and proteins. The lab's research takes place at the National Institute of Advanced Industrial Science and Technology (AIST). The lab aims to put the technologies it develops into practical use in collaboration with companies, and also seeks to apply them to developing nucleic acid reference materials and to international standardization. The environment allows a wide range of activities, from research and development to commercialization through collaboration with companies and international standardization.
Ayako Suzuki, Professor
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The Suzuki (Ayako) Lab uses the latest large-scale sequencing technologies to analyze cancer genomes and multi-omics data, aiming to clarify the characteristics of cancer cells. Its analyses focus in particular on lung cancer. The lab carries out both experiments and computational analysis in-house, and aims to develop new methods for classifying cancers. It holds a joint lab seminar once a week and a group meeting once a week.
Yoichiro Kamatani, Professor
0 student voices
The Kamatani Lab analyzes human biological big data, such as genomic and omics data, based on statistical genetics and learning theory. A trait is a characteristic that distinguishes an individual, such as appearance, personality, blood test values, or disease. Traits that cannot be explained by a handful of genes are called "complex traits," and the lab approaches the question of what they really are through data analysis. In an era when genomic and omics information is used in medicine and society, the lab also aims to train people who can work in this field.
Masahide Seki, Project Associate Professor
0 student voices
The Seki Lab develops sequencing-based omics analysis methods, along with methods for analyzing the resulting data. Genes are regulated at many levels, including the genome, epigenome, and transcriptome, before they function as proteins. Working mainly with humans and mice, the lab aims to clarify how this regulation of gene function works. Using the methods it has developed, along with approaches such as single-cell analysis, the lab also studies a range of diseases, including cancer.
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