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1,294 labs · 618 student voices
Kazuhiro Nakayama, Associate Professor
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The Nakayama Lab studies how diversity in human physiological traits has been shaped over time. In particular, it focuses on the relationship between the genetic adaptation of ancient people to environmental challenges such as cold and famine, and the diseases that are common in society today. The lab combines experiments that measure physiological traits, measurement of DNA sequences and chemical modifications, and population genetic analyses.
Shinichiro Maruyama, Associate Professor
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The Maruyama Lab studies photosymbiosis, in which photosynthetic organisms live together with other organisms. As in the case of corals and their symbiotic algae (Symbiodiniaceae, or zooxanthellae), symbiosis can give rise to new ways of living, and plant chloroplasts are thought to be one such example. The lab approaches its research from two directions: elucidating how symbiosis began, and understanding the diversity of symbioses that are occurring today.
Ken Naito, Visiting Professor
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The lab studies how wild plants growing along the seashore became tolerant of salt damage. Agriculture uses far more fresh water than the amount supplied by rainfall, so salt-tolerant crops are essential for developing crops that can be grown with seawater. The lab is located in the Genetic Resources Center at NARO (National Agriculture and Food Research Organization), where it also sequences the genomes of conserved crops and investigates the origins of crop cultivation.
Kazuya Tsuchihara, Visiting Professor
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Tsuchihara Lab studies cancer by combining clinical information gathered at the National Cancer Center with large-scale analytical data. The lab integrates data such as genomes, transcriptomes, and microbiomes obtained from patient specimens and cell models to draw out new knowledge. To do so, it uses bioinformatics techniques, including designing data-processing pipelines and building databases.
Umeharu Ohto, Professor
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Ohto Lab studies structural biology, which aims to understand how biomolecules such as proteins work by examining their three-dimensional structures. In biology, form and function are closely linked, and the shape of a molecule determines how it binds to other molecules. Using X-ray crystallography and cryo-electron microscopy, the lab investigates molecular shapes, which cannot be seen with the naked eye, at near-atomic resolution.
Masahiro Yasunaga, Visiting Professor
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The Yasunaga Lab researches the development of new anticancer drugs, centered on drug delivery systems (DDS) that deliver drugs only to the cancerous region. The lab focuses on developing antibody therapeutics, in which a drug or radioactive substance is attached to an antibody that targets cancer cells, as well as antibodies that direct T cells toward cancer. Using molecular imaging and mass spectrometry, the lab visualizes how drugs reach their targets and how they act inside the body as it advances its research.
Naoki Matsumoto, Associate Professor
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The Matsumoto Lab studies how innate immune cells distinguish self from non-self, and how this prevents attacks on the body's own tissues. In innate immunity, inhibitory receptors that recognize self are thought to prevent attacks on the normal body. The lab aims to identify the self molecules recognized by inhibitory receptors and to control innate immune responses using antibodies against these receptors.
Sachihiro Matsunaga, Professor
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The Matsunaga Lab studies the mechanisms behind plants' ability to regenerate and to withstand environmental stress. The lab investigates how processes are coordinated inside the plant cell nucleus, focusing on chromatin dynamics. It also develops new imaging technologies for observing plants, including a technique that makes plants transparent within a few hours. Using synthetic biology approaches, the lab is also taking on the challenge of creating animal cells capable of photosynthesis.
Higaki Takumi, Professor
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The Higaki Lab studies how structures inside plant cells are organized in an orderly way, and how the cells respond to changes in their environment. The lab's research rests on live-cell imaging, which continuously films living cells under a microscope, and on image analysis, which turns images into numerical data. The lab values "interdisciplinary integration" (gakuyugo): it is not limited to life sciences, and incorporates the ideas and methods of other fields such as information science and mathematical sciences.
Shoji Kawamura, Professor
0 student voices
The Kawamura Lab studies the evolution of genes involved in the senses in humans, wild primates, and fish. The lab investigates how the genes for sensor proteins (receptors) for color vision, olfaction, and the senses of bitter, sweet, and umami tastes have diversified among species. The lab's research crosses disciplinary boundaries, ranging from molecular biology and population genetics to behavioral ecology, which examines the behavior of wild monkeys. For many years, the lab has been conducting field research on wild monkeys in a national park in Costa Rica.
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