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13 labs · 0 student voices
Faculties at Waseda University ›
Kyojiro Nambu, Associate Professor
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The Nambu Lab conducts research that aims to solve problems found in medical practice through the power of engineering. To date, the lab has developed quantitative diagnostic imaging methods and technologies that reduce X-ray radiation exposure, and has co-proposed "Advanced Engineering Surgery" as a field of surgery for making full use of the outcomes of engineering. It has carried out research and development on information-guided surgical devices, surgical safety engineering, and transplantation device engineering. The lab regards medical regulatory science as a methodology for pursuing fair regulation, which is essential for turning technology into products and making them widely available.
Ken Masamune, Professor
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The Masamune Lab has consistently worked on developing advanced therapeutic devices that assist surgery. It has developed surgical navigation robots that move while MRI and other images are being acquired, augmented reality systems that overlay medical images directly onto the patient, and new endoscopic devices that safely observe and treat deep inside the body. At the joint graduate school, the lab conducts research closer to clinical practice from within the medical school, and focuses on deepening regulatory science, which is essential for bringing research results to market. The lab welcomes students interested in the development and evaluation of medical device products.
Masayuki Yamato, Professor
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The Yamato Lab studies regenerative medicine, with tissue engineering and stem cell biology as its two pillars. Regenerative medicine is a field that combines stem cell biology with tissue engineering, which reassembles the structure of tissues from cultured cells. Whereas molecular biology tries to understand life by breaking organisms down into their parts, the lab seeks to understand life through the practice of building tissues. Because this is an entirely new kind of medicine with no existing models, and because the lab believes that preparing the social environment is also important, it aims to build its own regulatory science.
Atsuko Deguchi, Professor
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The Deguchi Lab develops therapeutic drugs that prevent or suppress cancer metastasis. Cancer is the leading cause of death in Japan, and metastasis to distant organs is thought to be its main cause. Through basic research, the lab investigates the mechanisms of the microenvironment that forms around cancer. Based on the clues found there, it develops new forms of drugs such as small molecule compounds, multivalent peptides, and antibodies. At the same time, it also works on developing diagnostics for stratifying patients, as well as validation models that assume actual clinical settings.
Manabu Tamura, Associate Professor
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The Tamura Lab applies experience gained in neurosurgical practice to research on the evaluation of medical devices and drugs. Its work has covered functional neurosurgery, stereotactic radiotherapy, awake surgery in brain tumor operations, and the assessment of higher brain function to support patients' return to society after surgery. Drawing on experience with investigator-initiated clinical trials and with device development that combines medicine and engineering, the lab focuses on building mechanisms that allow clinical research to proceed smoothly. From a standpoint that integrates the humanities and the sciences, the lab builds the academic foundations of regulatory science and works on human resource development through collaboration among industry, government, and medicine.
Takeo Kubo, Professor
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The Kubo Lab works on two themes: information transmission in honeybees and organ regeneration in Xenopus. In both, the lab uses mechanisms that living things already possess as clues, and aims to reproduce or reawaken them in the laboratory. In honeybees, the lab investigates the neural excitation that occurs in the higher brain center during the waggle dance, which bees use to tell nestmates where a food source is. In Xenopus, the lab uses the regenerative ability found only in larvae as a clue, and seeks to artificially restore in adults the organ regeneration ability they have lost.
Etsuro Ito, Professor
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The Ito Lab begins its research by accurately measuring the physical quantities that living things make use of, such as force, heat, and electromagnetic waves. Because the lab believes that the advancement of biology itself has been supported by the development of measurement methods, it also works on developing new ways of measuring. Centered on methods for detecting very small amounts of protein, the lab covers early diagnosis of infectious diseases and cancer, human brain activity and pain, and learning and memory in snails. The lab has collaborations with universities and research institutions in Japan and abroad, and graduate students take part in them.
Takashi Kato, Professor
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The Kato Lab studies how blood cells are produced, that is, hematopoiesis. While knowledge about humans and mice has accumulated, our understanding of the diversity and universality of hematopoiesis across vertebrates in general has not advanced. In addition to mammals, the lab incorporates Xenopus and medaka, and builds new model systems for analyzing hematopoiesis using omics analysis, genome editing, and other approaches. The venues for setting up collaborations and sharing results span both basic biology and clinical medical science.
Kintake Sonoike, Professor
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The Sonoike Lab studies the mechanisms of photosynthesis, which uses light energy to convert carbon dioxide into organic matter. The main reaction pathways and components of photosynthesis are already known, but it is still unclear how this elaborate system is assembled and how it is remodeled when the environment changes. The lab tries to answer this question using the model plant Arabidopsis thaliana, the model photosynthetic organism cyanobacteria, and chilling-sensitive plants such as cucumber. Because photosynthesis in nature is limited by environmental factors, the lab investigates the survival strategies of plants through the relationship between photosynthesis and environmental factors.
Motoki Tominaga, Professor
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The Tominaga Lab studies the mechanisms that transport materials inside plant cells. Plants cannot move from the place where they take root, so they must sense their surroundings and grow to a size and shape suited to them. When plant cells are observed under a microscope, an active intracellular movement called cytoplasmic streaming can be seen. It occurs when the motor protein myosin moves along actin, a component of the cytoskeleton. Using techniques in cell biology, molecular biology, and live imaging, the lab aims to understand plants in an integrated way, from the molecular level to the level of the whole organism.
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