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Other departments in Graduate School of Advanced Science and Engineering ›Faculties at Waseda University ›

Takeo Kubo, Professor
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The Kubo Lab works on two themes: information transmission in honeybees and organ regeneration in Xenopus. In both, the lab uses mechanisms that living things already possess as clues, and aims to reproduce or reawaken them in the laboratory. In honeybees, the lab investigates the neural excitation that occurs in the higher brain center during the waggle dance, which bees use to tell nestmates where a food source is. In Xenopus, the lab uses the regenerative ability found only in larvae as a clue, and seeks to artificially restore in adults the organ regeneration ability they have lost.

Etsuro Ito, Professor
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The Ito Lab begins its research by accurately measuring the physical quantities that living things make use of, such as force, heat, and electromagnetic waves. Because the lab believes that the advancement of biology itself has been supported by the development of measurement methods, it also works on developing new ways of measuring. Centered on methods for detecting very small amounts of protein, the lab covers early diagnosis of infectious diseases and cancer, human brain activity and pain, and learning and memory in snails. The lab has collaborations with universities and research institutions in Japan and abroad, and graduate students take part in them.

Takashi Kato, Professor
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The Kato Lab studies how blood cells are produced, that is, hematopoiesis. While knowledge about humans and mice has accumulated, our understanding of the diversity and universality of hematopoiesis across vertebrates in general has not advanced. In addition to mammals, the lab incorporates Xenopus and medaka, and builds new model systems for analyzing hematopoiesis using omics analysis, genome editing, and other approaches. The venues for setting up collaborations and sharing results span both basic biology and clinical medical science.

Kintake Sonoike, Professor
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The Sonoike Lab studies the mechanisms of photosynthesis, which uses light energy to convert carbon dioxide into organic matter. The main reaction pathways and components of photosynthesis are already known, but it is still unclear how this elaborate system is assembled and how it is remodeled when the environment changes. The lab tries to answer this question using the model plant Arabidopsis thaliana, the model photosynthetic organism cyanobacteria, and chilling-sensitive plants such as cucumber. Because photosynthesis in nature is limited by environmental factors, the lab investigates the survival strategies of plants through the relationship between photosynthesis and environmental factors.

Motoki Tominaga, Professor
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The Tominaga Lab studies the mechanisms that transport materials inside plant cells. Plants cannot move from the place where they take root, so they must sense their surroundings and grow to a size and shape suited to them. When plant cells are observed under a microscope, an active intracellular movement called cytoplasmic streaming can be seen. It occurs when the motor protein myosin moves along actin, a component of the cytoskeleton. Using techniques in cell biology, molecular biology, and live imaging, the lab aims to understand plants in an integrated way, from the molecular level to the level of the whole organism.

Shinpei Yoshitake, Professor
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The Yoshitake Lab studies how carbon and nitrogen cycle through terrestrial ecosystems such as forests. Carbon and nitrogen move back and forth between living organisms and the external environment while changing form, and the lab observes and describes the pathways and amounts of this cycling through field surveys. Much of what is still unknown about these cycles lies in the soil beneath our feet, so the lab focuses on the functions of soil microbial communities. Field surveys are the foundation of the lab's work, and they are combined with laboratory and cultivation experiments to confirm the detailed mechanisms.

Masaki Hoso, Associate Professor
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The Hoso Lab studies the evolutionary mechanisms that have produced the rich biodiversity we see today. Evolution is described by the physical processes involved in the inheritance of genetic material, the chance events that accompany them, and the various constraints that arise within the complex system that is life. Grounded in natural history research based on field observation and specimens, the lab pursues evolutionary biology, with a particular focus on the evolutionary ecology of animals. A particular focus is left-right asymmetry in body structure and behavior.

Yoshiki Nishimura, Associate Professor
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The Nishimura Lab studies the functions of chloroplasts and mitochondria, building on the methods of molecular genetics. Chloroplasts and mitochondria are thought to have originated from independent bacteria that entered into symbiosis with the ancestors of eukaryotic cells, and they still have their own DNA and gene expression machinery. This DNA binds to proteins to form a structure called the nucleoid, but its detailed structure and regulatory mechanisms are still not understood. Using the unicellular green alga Chlamydomonas and other model organisms, the lab combines microscopy, genetics, and biochemistry.
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