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Kubo Lab
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The lab studies how living things work by learning from the honeybee brain and frog regeneration, and then reproducing those mechanisms.
AboutAbout the lab
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The Kubo Lab works on two themes: information transmission in honeybees and organ regeneration in Xenopus.
In both, the lab uses mechanisms that living things already possess as clues, and aims to reproduce or reawaken them in the laboratory.
In honeybees, the lab investigates the neural excitation that occurs in the higher brain center during the waggle dance, which bees use to tell nestmates where a food source is.
In Xenopus, the lab uses the regenerative ability found only in larvae as a clue, and seeks to artificially restore in adults the organ regeneration ability they have lost.
Key terms
- waggle dance
- A figure-eight movement that honeybees perform inside the hive. It tells nestmates the distance and direction to a food source.
- Mushroom body
- A higher brain center in insects. It is thought to play roles in learning, memory, and the integration of sensory information.
- Organ regeneration
- Rebuilding a lost part of the body as an organ with the same form and function as the original.
NewsLab news
A Professor took up the post, and the lab was launched in the Department of Life Science and Technology
The Professor received the 2024 Zoological Society of Japan Award
ResearchResearch themes
The Kubo Lab seeks to understand the mechanisms that living things naturally possess by reproducing or reawakening them through human intervention. It pursues two themes: mimicking the honeybee waggle dance, and engineering the reactivation of organ regeneration in Xenopus.
*Illustrative imageMimicking the honeybee waggle dance
Honeybees tell their nestmates the distance and direction of a food source through the waggle dance. While a bee is dancing, a subset of neurons called Kenyon cells is excited in the higher brain center, the mushroom body. The lab investigates what kind of information processing this excitation represents, and aims in the future to reproduce the waggle dance in the laboratory.
*Illustrative imageOrgan regeneration in Xenopus
Xenopus larvae can regenerate their tails, but adults can no longer regenerate their limbs. The loss of regenerative ability during development is also seen in mammals. Based on the molecular mechanisms involved in organ regeneration in larvae, the lab aims to artificially restore regenerative ability in adults.
MembersFaculty
The members of the Kubo Lab consist of faculty and graduate students.
- ProfessorTakeo Kubo
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “CSIRO ScienceImage 7113 Honey bee comb showing cells” Nick Pitsas, CSIRO / CC BY 3.0 (cropped)
- Mimicking the honeybee waggle dance: “Apis mellifera - Melilotus albus - Keila” Ivar Leidus / CC BY-SA 4.0 (cropped)
- Organ regeneration in Xenopus: “XenopusLaevis 6473” Davefoc / CC BY-SA 4.0 (cropped)
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