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102 labs · 0 student voices
Faculties at The University of Osaka ›
Yuki Kondo, Professor
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The Plant Cell Fate Regulation Lab studies how plant cells determine their own fate, using vascular tissue, which transports water, sugars, and other substances, as its subject. When leaves are soaked in a culture medium containing hormones, vascular cells can be produced with high efficiency within a few days. The lab developed this differentiation induction system, called VISUAL, itself and uses it in its research. The lab is also developing imaging that uses the mechanisms of bioluminescent organisms such as fireflies to capture changes in cell fate over time. The plants used as materials include Arabidopsis, tomato, tobacco, ginkgo, the moss Physcomitrium patens, and the liverwort Marchantia polymorpha.
Ginga Shimakawa, Professor
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The Plant Physiology Lab carries out a wide range of research on plants, algae, and other organisms, centered on photosynthesis. The backbone-like machinery that supports photosynthesis is similar across many organisms, but the reactions surrounding it strongly reflect the characteristics of each organism. By studying these reactions surrounding photosynthesis, the lab seeks to understand the ways of life of plants, algae, bacteria, and other organisms. Current research themes include the photosynthetic quotient, leaf senescence, the internal structure of chloroplasts, and the symbiosis between corals and zooxanthellae.
Hidetaka Furuya, Professor
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The Animal Morphology Lab conducts natural history research on dicyemids, mesozoans that live in the renal sacs of cephalopods. Building on taxonomy, the lab investigates them from many perspectives, including morphology, development, phylogeny, ecology, evolution, and genomics. Viewing the renal sac as a small natural laboratory, the lab explores how dicyemids live in this environment and what interactions occur among coexisting species. The lab also conducts natural history research on animal groups other than dicyemids, aiming to understand the nature of living organisms.
Asako Shindo, Professor
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The Organ Morphogenesis Regulation Lab uses Xenopus embryos and tadpoles to study how the shapes of tissues and organs are formed. The body is made of tissues and organs that embody the beauty of form designed to maximize function (functional beauty). These shapes are assembled during development through the precise movements of individual cells, but much of the mechanism, including what gives the cells their instructions, remains a mystery. The lab aims to uncover the mechanisms by which cells form and control shape while coping with stress from the environment. On the lab's website, it is presented under the name "Shindo Lab."
Sakiko Shiga, Professor
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The Comparative Neurobiology Lab studies how invertebrates such as insects and mollusks process information about time in their brains and nervous systems. Using the innate circadian clock, the lab investigates photoperiodism, the mechanism by which organisms read the season from photoperiod information, as well as the mechanisms behind the unique behaviors timed by the circadian clock. Research subjects include the bean bug (Riptortus pedestris), the large black chafer (Holotrichia parallela), which has a circabidian rhythm with a 48-hour period, and the great pond snail (Lymnaea stagnalis), a freshwater snail. On the lab's website, it is presented under the name "Shiga Lab."
Chikashi Obuse, Professor
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The Chromosome Structure and Function Lab studies at the molecular level how genetic information is packaged in the nucleus, inherited, and regulated in its expression. DNA, the blueprint that builds the body, is a long molecule that reaches about 2 meters in humans, yet it fits inside a nucleus about 10 µm in diameter. This molecule is accurately passed on to tens of trillions of cells, and its expression is tightly regulated as the body develops. The lab's research results page introduces papers on the regulation of stem cell differentiation and the repair of broken DNA.
Naotada Ishihara, Professor
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The Cellular Life Science Lab studies the "dynamics" of mitochondria, which change shape through fusion and fission. The lab approaches the topic from two sides: the molecular mechanisms that change membrane shape, and the significance of these processes, including their roles in a healthy body and their effects in disease. The lab combines cell culture experiments, biochemical experiments using isolated mitochondria and purified proteins, and experiments involving mouse genes. On the lab's website, it is introduced as the "Ishihara Lab."
Takuro Nakagawa, Professor
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The Molecular Genetics Lab studies how chromosomes, which carry genetic information, are kept stable and accurately passed on to daughter cells. Inside the cell nucleus, DNA binds to histones to form nucleosomes, which are further organized into higher-order chromatin structures. The lab aims to clarify the molecular mechanisms by which reactions on chromosomes, such as DNA replication, recombination, repair, transcription, and chromatin regulation, work together to maintain chromosome stability. The lab uses fission yeast and cultured human cells in its research.
Yoshitaka Matsuo, Professor
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The Dynamic Molecular Biochemistry Lab focuses on translation, the endpoint of the central dogma, and studies the dynamic process by which nascent chains produced by translation mature into functional proteins. The lab also explores how giant molecular complexes such as the ribosome are assembled with precision inside the cell. Focusing on quality control mechanisms, the lab investigates how translation becomes more prone to stalling with aging, leading to the accumulation of abnormal proteins. The lab combines multi-omics, in vitro reconstitution systems, high-speed AFM, cryo-EM, and other analyses in its research.
Takahide Kon, Professor
0 student voices
The Cell Architecture Lab studies intracellular transport, the mechanism that delivers what is needed to where it is needed, at the time it is needed, inside the cell. The lab is a group of researchers specializing in structural biology, protein science, and cell biology, who investigate the topic from many angles at the levels of molecular structure, supramolecular complexes, and the cell. The lab's website says it focuses on the working mechanism of dynein, a giant protein nanomachine that plays an important role in transport in the brain and nervous system. At the undergraduate level, the lab mainly accepts fourth-year students of the Department of Biological Sciences as graduation research students. Note that the news items and member list on the lab website date from around 2018.
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