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Comparative Neurobiology Lab
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The lab studies how insects and snails use clocks to read the seasons.

AboutAbout the lab
Brain and clock mechanisms by which organisms read the seasons
The Comparative Neurobiology Lab studies how invertebrates such as insects and mollusks process information about time in their brains and nervous systems.
Using the innate circadian clock, the lab investigates photoperiodism, the mechanism by which organisms read the season from photoperiod information, as well as the mechanisms behind the unique behaviors timed by the circadian clock.
Research subjects include the bean bug (Riptortus pedestris), the large black chafer (Holotrichia parallela), which has a circabidian rhythm with a 48-hour period, and the great pond snail (Lymnaea stagnalis), a freshwater snail.
On the lab's website, it is presented under the name "Shiga Lab."
Key terms
- Photoperiodism
- The property of reading the season from information on the lengths of day and night (photoperiod) and changing behavior or bodily state accordingly
- Circadian clock
- An innate clock in living things that keeps the rhythm of behavior and other processes
- Circabidian rhythm
- A behavioral rhythm with a 48-hour period found in the large black chafer
NewsLab news
A paper on corazonin peptide and neurons in the bean bug was published in Journal of experimental biology
A paper by a graduate on PTTH and PDF neurons in the flesh fly Sarcophaga similis was published in Journal of comparative physiology A
A master's student won a Presentation Award for Young Scientists at the International Congress of Entomology (ICE2024)
ResearchResearch themes
Using invertebrates such as insects and mollusks, the lab investigates how the brain and nervous system process information about time and the environment. The main topics are the mechanism by which the circadian clock is used to read the season from photoperiod, the mechanisms of behaviors timed by the circadian clock, and the neural mechanisms by which the brain processes environmental information.
View More ↗MembersFaculty
The Comparative Neurobiology Lab consists of faculty, doctoral, master's, and undergraduate students, and a secretary.As of 2026
- ProfessorSakiko Shiga
- LecturerYoshitaka Hamanaka
- LecturerAisa Sakaguchi
- Assistant ProfessorHisashi Tobita
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Riptortus pedestris” Phonon.b / CC BY-SA 4.0 (cropped)
- Related lab (生命機能グループ研究室): “Pendulum clock by Jacob Kock, antique furniture photography, IMG 0931 edit” Christoph Braun / CC0 (cropped)
- Related lab (分子発生学研究室): “Confocal Microscope” Mark from Edinburgh, United Kingdom / CC BY-SA 2.0 (cropped)
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): “Fluorescence microscopy of stage 24 squid embryo with ZEISS Celldiscoverer )” ZEISS Microscopy from Germany / CC BY 2.0 (cropped) - Related lab (植物生理学研究室): “Photosynthesis System analysing a maize leaf” Viséan / CC BY-SA 4.0 (cropped)
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