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Faculties at The University of Osaka ›

Kosuke Namba, Professor
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The Biomolecular Chemistry Lab studies the total synthesis of complex, scarce bioactive natural products, as well as the revegetation of poor alkaline soils and the elucidation of the mechanism of iron ion uptake. The lab also develops tools for elucidating mechanisms of action and functions, as well as organic synthetic reactions using transition metal catalysts and environmentally benign organic synthetic reactions. The lab started in April 2025 in the Department of Chemistry, Graduate School of Science, Osaka University.

Yasuhiro Kajihara, Professor
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The lab precisely synthesizes proteins with attached glycans (glycoproteins) and investigates what roles glycans play on proteins. Glycans attached to proteins vary in structure, so it is not easy to study the function of each individual glycan. To address this, the lab chemically synthesizes glycoproteins with uniform glycan structures. On the lab's website, it is introduced under the name "Kajihara Laboratory."

Atsushi Shimoyama, Associate Professor
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The lab studies naturally occurring organic compounds with biological activity, especially complex molecules that contain sugars. Focusing on glycoconjugates in the cell surface layer of bacteria, the lab determines their chemical structures and synthesizes them chemically. Lipopolysaccharide and peptidoglycan are substances involved in innate immunity in animals, and the lab also investigates the mechanisms by which they act.

Motohiro Nakano, Professor
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The center combines molecular-level insights with an entropy perspective to build a view of matter that is aware of its hierarchical structure. Based on its original calorimetric techniques, the center pursues joint research and collaborative frameworks with researchers, research institutions, and companies in Japan and abroad. Starting as the Chemical Thermodynamics Laboratory in 1979, it was reorganized several times and took its current name in 2019. The center's full-time faculty conduct research and education as a cooperating group of the Department of Chemistry and as a concurrent-appointment group in the undergraduate program.

Takashi Yoshimura, Professor
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The Isotope Chemistry Lab builds on research in coordination chemistry and studies a wide range of metal elements, including radioactive elements. The lab works on synthesizing metal complexes that emit radiation and light, actinide chemistry, and developing chemical separation methods for elements such as astatine for nuclear medicine therapy. Its research themes also include the behavior of radioactive materials in the environment and analytical chemistry using muonic atoms. The lab is located in the Toyonaka Branch of the Radioisotope Research Center on Toyonaka Campus, and lab tours are held at any time for undergraduate, master's, and doctoral students alike.

Michio Okada, Professor
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The Particle Beam Chemistry Lab studies the elementary processes of chemical reactions that particle beams of atoms and molecules induce on solid surfaces, with the aim of controlling them. While developing its own advanced instruments, the lab conducts physical chemistry research rooted in making things (monozukuri). The lab also develops original surface analysis instruments that use particle beams. The lab belongs to the Institute for Radiation Sciences at The University of Osaka and is a cooperating division of the Department of Chemistry, Graduate School of Science.

Atsushi Toyoshima, Professor
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The Radiation Science Lab conducts research on radiation and radioisotopes with social applications and the solution of social issues in mind. The research is carried out through joint research with researchers in other fields and with private companies. Its main pillars are chemical research on nuclear medicine therapy using short-lived radioisotopes (RIs), and research related to the decommissioning of the Fukushima Daiichi Nuclear Power Plant and the recovery of the Hamadori area of Fukushima Prefecture. In nuclear medicine therapy, the lab deals with RI production methods, separation and purification, methods for labeling drugs, and the development of new drugs.

Kazuko Kaneda-Nakashima-Nakashima, Professor
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The Radiation Biochemistry Lab aims to develop nuclear medicine therapeutics by labeling molecules of various sizes with short-lived radionuclides and evaluating their functions. The lab also analyzes the function of LAT1, an amino acid transporter whose expression is specifically induced in cancer cells, in order to clarify why this molecule is expressed in cancer and to help develop better therapeutics. In collaboration with the Graduate School of Medicine, the Graduate School of Engineering, the Institute for Radiation Sciences, and the Research Center for Nuclear Physics, the lab is involved in every step, from producing and separating nuclides to synthesizing and labeling compounds and evaluating them in cells and experimental animals. Regardless of which undergraduate faculty students come from, the lab values learning a variety of experimental methods and discovering one's own aptitude.

Kazuya Kabayama, Professor
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The Radiation Chemical Biology Lab studies drug development for targeted alpha therapy (TAT) and the functional analysis of sugar- and lipid-related molecules. Targeted alpha therapy is a drug-based treatment that delivers nuclides emitting high-energy alpha particles to cancer cells and kills them, and it is attracting attention as a new treatment for intractable cancers. The lab develops drug candidate compounds labeled with astatine-211 and conducts research with a view to a first-in-human clinical trial. In addition, in collaboration with synthetic organic chemists, the lab creates fluorescently labeled bioactive molecules and investigates the functions of sugar- and lipid-related molecules involved in diseases such as infections, cancer, and diabetes.

Keisuke Miyakubo, Associate Professor
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The Museum of Osaka University Advanced Collections Research Lab aims to apply physical chemistry methods to cultural heritage science, conservation science, and exhibition science. In cultural heritage science, the lab explores topics such as identifying the production date and provenance of cultural properties and reproducing how they were made. In conservation science, it studies cultural property materials such as cellulose to help preserve collection materials, and in exhibition science, it aims to reconcile the exhibition and use of materials with their preservation. The lab also researches building digital databases of academic collection information held by the museum and by various units of Osaka University, working to make it available to researchers in Japan and abroad.
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