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Radiation Science Lab
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The lab studies nuclear medicine therapy using radioisotopes and the decommissioning of the Fukushima Daiichi Nuclear Power Plant.
AboutAbout the lab
Research on radiation and radioisotopes
The Radiation Science Lab conducts research on radiation and radioisotopes with social applications and the solution of social issues in mind.
The research is carried out through joint research with researchers in other fields and with private companies.
Its main pillars are chemical research on nuclear medicine therapy using short-lived radioisotopes (RIs), and research related to the decommissioning of the Fukushima Daiichi Nuclear Power Plant and the recovery of the Hamadori area of Fukushima Prefecture.
In nuclear medicine therapy, the lab deals with RI production methods, separation and purification, methods for labeling drugs, and the development of new drugs.
Key terms
- RI
- Abbreviation of radioisotope. Those with a short half-life are called short-lived RIs.
- Astatine
- One of the halogen elements, like iodine. It has no stable isotopes.
- Alpha rays
- High-energy helium nuclei. They stop within a short distance in matter.
- Fuel debris
- Nuclear fuel that became extremely hot in the accident, then cooled and solidified together with the surrounding structures.
NewsLab news
A paper by Project Professor Yokoyama and colleagues was published in Radiochimica Acta
A paper by Prof. Toyoshima and colleagues was published in Nuclear Medicine and Biology
A paper by Associate Professor Murakami and colleagues was published in Journal of Nuclear Science and Technology
A paper by Prof. Toyoshima and colleagues was published in the Journal of the Japan Society of Radiation Safety Management
The start of a Phase 1 investigator-initiated clinical trial of astatine PSMA-5 was announced
ResearchResearch themes
The Radiation Science Lab conducts research on radiation and radioisotopes with social applications and the solution of social issues in mind. It works on chemical research on short-lived radioisotopes (RIs) for nuclear medicine therapy, and on research related to the decommissioning of the Fukushima Daiichi Nuclear Power Plant and the recovery of the Hamadori area of Fukushima Prefecture.
*Illustrative imageAlpha therapy using astatine
The lab studies a therapy in which astatine-211, a short-lived RI, is chemically attached to a drug that accumulates in cancer cells, and alpha rays destroy the cancer cells. It is developing new labeling methods and labeled compounds, as well as accelerator-based production methods.
*Illustrative imageBeta therapy using scandium
Because lutetium-177 is produced in nuclear reactors, domestic production is difficult, so the lab focuses on scandium-47, which can be produced with an accelerator. In joint research with the Research Center for Electron Photon Science, Tohoku University, it studies production methods, separation and purification methods, and compound labeling methods.
*Illustrative imageTracking drugs by making them radioactive
The lab aims to make the accumulation and movement of drugs in the body visible by making a drug radioactive so that it becomes an RI, and imaging the gamma rays it emits. It studies making existing drugs such as cisplatin, as well as gold nanoparticles, radioactive using neutrons in a nuclear reactor.
*Illustrative imageDetecting radioactive dust for decommissioning
The lab is developing, jointly with the Toyoda Lab at the Forefront Research Center, Graduate School of Science, an analytical method to quickly detect the radioactive fine particles (dust) thought to be released when fuel debris is removed. Using an instrument that identifies fine particles one by one by mass, it conducts detection tests with simulated uranium dust.
MembersFaculty
The members of the Radiation Science Lab are the faculty, doctoral, master's, and undergraduate students, and administrative staff.As of 2026
- ProfessorAtsushi Toyoshima
- Project ProfessorAkihiko Yokoyama
- Associate ProfessorMasashi Murakami
- Project Associate ProfessorYuichiro Kadonaga
- Project Assistant ProfessorFeng Yin
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Radiation Assessment Detector for Curiosity Rover” NASA / Public domain (cropped)
- Alpha therapy using astatine: “First Image of Astatine - English Label” NuclearAlex / CC BY 4.0 (cropped)
- Beta therapy using scandium: “Cyclotron patent” Ernest O. Lawrence / Public domain (cropped)
- Tracking drugs by making them radioactive: “Molecubes SPECT uCT and PET” Adville / CC BY-SA 4.0 (cropped)
- Detecting radioactive dust for decommissioning: “HWCTR Decommissioning ( )” ENERGY.GOV / Public domain (cropped)
- Related lab (Radiation Chemical Biology Lab): “Radiochemistry Laboratory ( )” IAEA Imagebank / CC BY 2.0 (cropped)
- Related lab (Radiation Biochemistry Lab): “Isotope laboratory at the National Institutes of Health ( )” NIH Image Gallery from Bethesda, Maryland, USA / Public domain (cropped)
- Related lab (Museum of Osaka University Advanced Collections Research Lab): “Mycenaean pottery in the National Archaeological Museum of Athens” 作者不詳 / CC0 (cropped)
- Related lab (Biomolecular Chemistry Lab): “Round bottom flasks cork stand” real name: Nadina Wiórkiewicz pl.wiki: Nadine90 commons: Nadine90 / CC BY-SA 3.0 (cropped)
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