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23 labs · 0 student voices
Other departments in Faculty of Pharmaceutical Sciences ›Faculties at Chiba University ›
Hiroto Kawashima, Professor
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The Immunology and Microbiology Lab studies how the immune system works, focusing on the roles of glycans. Combining immunology, microbiology, and glycobiology, it clarifies the workings of the immune system at the molecular level. It aims to apply this knowledge to developing treatments for allergies, inflammatory diseases, infections, cancer, and other conditions that arise when these mechanisms break down.
Akiko Takaya, Professor
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The Infection Control Lab, part of the Department of Genome-Based Drug Discovery at the Graduate School of Pharmaceutical Sciences, Chiba University, studies the mechanisms that suppress bacterial infection. In relation to the host's immune function, it investigates the molecular mechanisms that control bacterial infection. It also analyzes how antibiotic-resistant bacteria isolated in clinical settings acquire resistance, and the strategies bacteria use to adapt to and survive harsh environments. Another focus is how natural compounds with antimicrobial activity act on bacteria.
Manabu Nakayama, Professor
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The Genetic Drug Discovery Lab is a collaborative chair (pharmacy) of Chiba University's Graduate School of Medical and Pharmaceutical Sciences, and its faculty members are affiliated with the Kazusa DNA Research Institute. The lab develops genome engineering technologies and uses them to create disease model mice. To identify genes associated with common human diseases, the lab is building a pipeline for producing conditional knockout mice. The lab also conducts research to comprehensively investigate the functions of a group of very large proteins expressed in the nervous system.
Tomoya Uehara, Professor
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The Molecular Imaging Pharmaceutics Lab studies the development of radiopharmaceuticals, which are drugs that use radionuclides (RI). Depending on the type of radiation used, a radiopharmaceutical can serve either as a diagnostic agent that detects disease through imaging or as a therapeutic agent that treats cancer. For early diagnosis of cancer and early assessment of treatment effects, the lab is developing drugs that allow changes inside cells to be captured in images from outside the body. In collaboration with Osaka University and other institutions, the lab is also working on developing cancer therapeutics that use astatine-211, which emits alpha radiation.
Yasumitsu Ogra, Professor
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The Preventive Pharmacy Lab studies how chemical substances, especially metal compounds, affect human health. Even essential metals that the body needs are harmful in excess, and even toxic metals do not show toxicity below a certain concentration. The lab examines, step by step, how metals are taken up, transported, function, and are excreted in the body, aiming to clarify how the body regulates metals. The lab's facilities include instruments for elemental analysis, such as an ICP mass spectrometer and atomic absorption spectrophotometers.
Daisuke Nakajima, Professor
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The Environmental Risk Lab is a collaborative program of the Graduate School of Medical and Pharmaceutical Sciences (Pharmaceutical Sciences) at Chiba University, and its partner institution is the National Institute for Environmental Studies. The faculty's primary appointments are at the partner institution, the National Institute for Environmental Studies. The lab's field is the assessment of chemical exposure and the effects of that exposure on living organisms. Its research areas include developing methods for comprehensive analysis of exposure to many kinds of chemicals, including newly emerging ones, and developing human biomonitoring methods. Using analytical toxicology methods, the lab also works to clarify the metabolic mechanisms of metalloid elements.
Hiroyuki Nakamura, Professor
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The Pharmacodynamics Lab studies receptors and intracellular signal transduction to search for therapeutic targets and drug candidates for diseases. Many drugs in use today act on receptors or block ion channels. The lab focuses in particular on the pharmacological actions of molecules related to sphingolipids such as sphingosine and ceramide. It is also working on developing treatments for rare and intractable diseases such as Niemann-Pick disease type C and multiple sclerosis.
Hiroto Hatakeyama, Professor
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The Drug Science Lab studies next-generation drugs, focusing on how drugs move within the body and cells and where they end up. Its subjects are antibody drugs such as immune checkpoint inhibitors used in cancer immunotherapy, and nucleic acid drugs that use lipid nanoparticles. Much remains unknown about how drug effects and side effects arise, so the lab pursues both basic research grounded in clinical problems and applied research aimed at practical use. The lab accepts inquiries about lab visits, but applicants from outside who wish to enter its graduate school are limited to those hoping to go on to a PhD.
Kosei Ito, Professor
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The Biopharmaceutics Lab studies the pharmacokinetics of drugs and drug candidate compounds (how they behave in the body) and their adverse effects, such as side effects. Even when no problems appear in test tubes or mice, unexpected side effects often emerge only once a drug is used in humans. The lab aims to clarify the mechanisms of side effects at the molecular level and, on that basis, to develop methods for predicting them in advance. It focuses in particular on injury to the liver, the central organ for drug metabolism and excretion.
Yuko Sekine, Professor
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The Pharmacy Practice Lab identifies problems that arise in pharmacists' work and conducts research to put evidence-based proper use of drugs into practice. In clinical practice, there are many drugs that have long been used without clear evidence, and many areas, such as managing side effects, where evidence has not been established. The lab believes it is essential for pharmacists, as scientists, to take part in drug therapy by presenting evidence. Through research, the lab aims to train clinical pharmacists who will be central to future drug therapy.
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