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Genetic Drug Discovery Lab
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The lab creates disease model mice through genome engineering to search for disease-causing genes.
AboutAbout the lab
Finding disease genes through genome engineering.
The Genetic Drug Discovery Lab is a collaborative chair (pharmacy) of Chiba University's Graduate School of Medical and Pharmaceutical Sciences, and its faculty members are affiliated with the Kazusa DNA Research Institute.
The lab develops genome engineering technologies and uses them to create disease model mice.
To identify genes associated with common human diseases, the lab is building a pipeline for producing conditional knockout mice.
The lab also conducts research to comprehensively investigate the functions of a group of very large proteins expressed in the nervous system.
Key terms
- Genome engineering technology
- Technology that rewrites targeted parts of an organism's genetic information (the genome)
- Disease model mouse
- A mouse engineered to reproduce a condition resembling a human disease, used to study how the disease works
- Conditional knockout mouse
- A mouse in which the function of a specific gene is turned off only in certain tissues or at certain times
ResearchResearch themes
The lab conducts research on developing genome engineering technologies and creating disease model mice. It also works on building a system for finding genes associated with common human diseases, and on analyzing the functions of a group of very large proteins expressed in the nervous system.
View More ↗MembersFaculty
The faculty members of the Genetic Drug Discovery Lab are affiliated with the Kazusa DNA Research Institute.As of 2026
- ProfessorManabu Nakayama
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “MPI-CBG inside of laboratory pl” Pleple2000 / CC BY-SA 3.0 (cropped)
- Related lab (Biopharmaceutics Lab): “Atenolol tablets (UK)” Whispyhistory / CC BY-SA 4.0 (cropped)
- Related lab (Pharmacy Practice Lab): “Julie Zinihite at the pharmacy at the National Referal Hospital in Honiara, Solomon Islands 2012. Photo- AusAID ( )” Department of Foreign Affairs and Trade / CC BY 2.0 (cropped)
- Related lab (Environmental Risk Lab): “Liquid chromatograph with a mass spectrometer operating on the principle of flight time in combination with a quadrupole analyzer (qTOF) in CAFIA laboratory, Czech Republic” Sarka Na kopci / CC BY-SA 4.0 (cropped)
- Related lab (Pharmacodynamics Lab): “Fluorescence.microscope2” Bioguy10 / CC0 (cropped)
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