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Hematology Lab
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A lab that pursues clinical care and research to overcome blood cancers.
AboutAbout the lab
Working to overcome hematopoietic disorders.
The Hematology Lab studies hematopoietic disorders such as leukemia, malignant lymphoma, and multiple myeloma.
Valuing the perspective of physicians who treat blood diseases, the lab aims to improve patients' prognosis and to conquer these diseases.
Hematology has close ties between basic research and clinical practice, so findings from basic research can readily be brought back to patients.
The lab works on education and on building an environment in which both clinical and basic research strengths are maximized.
Key terms
- Hematopoietic disorders
- Diseases that arise in the cells that produce blood, including leukemia, malignant lymphoma, and multiple myeloma
- Plasma cells
- Lymphocytes that produce antibodies. When they proliferate abnormally, they can cause diseases such as multiple myeloma
- Hematopoietic stem cell transplantation
- A treatment in which the cells that give rise to blood are transplanted to replace the body's blood-forming system
NewsLab news
The Hematology Lab was newly established at Chiba University Graduate School of Medicine
A presentation from the lab received an Encouragement Award at the 714th Kanto Regional Meeting of the Japanese Society of Internal Medicine
A presentation from the lab was selected for Best of JSM2026 at the 51st Annual Meeting of the Japanese Society of Myeloma
The lab received an Abstract Award at The 16th JSH International Symposium 2026
A paper from the lab was accepted by Rinsho Ketsueki (The Japanese Journal of Clinical Hematology)
ResearchResearch themes
Valuing the perspective of physicians who treat blood diseases, the lab pursues research with the goals of improving patients' prognosis and, further, conquering these diseases. Research and treatment of hematologic malignancies have advanced remarkably in recent years, and the lab aims to conduct research that contributes to clinical practice, however modestly.
*Illustrative imageElucidating the pathophysiology of POEMS syndrome
POEMS syndrome is a systemic disease that causes peripheral neuropathy, organ enlargement, and edema. Blood levels of vascular endothelial growth factor become abnormally high, but the cells that produce it have not been identified. The lab focuses on plasma cells in the bone marrow and investigates the molecular pathophysiology.
*Illustrative imageNew treatment strategies for multiple myeloma
In human myeloma, mutations in the demethylase UTX and the BRAF-V600E mutation are associated with poor prognosis. The lab generated mice in which Utx is deleted in mature B cells and the Braf-V600E mutation is introduced, and showed that they develop plasma cell tumors resembling myeloma.
*Illustrative imageClinical research on hematopoietic stem cell transplantation
The lab has been performing hematopoietic stem cell transplantation since its first case in 1986. It has built a regional network of hematology departments in Chiba Prefecture, holds regular conferences, and carries out joint research with a clinical research group centered on Chiba University Hospital.
MembersFaculty
The members of the Hematology Lab consist of faculty, staff physicians, graduate students, specialty residents, and hematopoietic cell transplant coordinators.As of 2026
- ProfessorEmiko Sakaida
- Clinical Associate ProfessorNaoya Mimura
- Clinical LecturerYusuke Takeda
- Clinical LecturerShokichi Tsukamoto
- Clinical LecturerNagisa Oshima
- Project Assistant ProfessorArata Ishii
- Project Assistant ProfessorShinichiro Matsui
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Connective Tissue Human Blood Leukocyte Survey ( )” Berkshire Community College Bioscience Image Library / CC0 (cropped)
- Elucidating the pathophysiology of POEMS syndrome: “Multinucleated plasma cell -- high mag” Nephron / CC BY-SA 3.0 (cropped)
- New treatment strategies for multiple myeloma: “Wright's staining of multiple myeloma, plasmablastic type” Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: None Mikael Häggström, M.D.Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance). / CC0 (cropped)
- Clinical research on hematopoietic stem cell transplantation: “Bone marrow transplant” MariaCisnerosMartin / CC BY-SA 4.0 (cropped)
- Related lab (Cellular and Molecular Medicine Lab): “Molecular Biology Laboratory, reflections - geograph.org.uk - 3763234” John Sutton / CC BY-SA 2.0 (cropped)
- Related lab (Allergy and Clinical Immunology Lab): “Eosinophils in Peripheral Blood Smear ( )” Ed Uthman from Houston, TX, USA / CC BY 2.0 (cropped)
- Related lab (Innovative Regenerative Medicine Lab): “Hematopoietic Stem Cell (NIH BioArt 200)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (Tumor Pathology Lab): “Scanning electron microscope - UFCH JH (2020) 01” Tadeáš Bednarz / CC BY-SA 4.0 (cropped)
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