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細胞分子医学
Showing the original Japanese · View translation
遺伝子のオン・オフを決めるしくみから、発生とがん治療に迫る研究室。
AboutAbout the lab
遺伝子の切り換えから、発生と病気を読み解く。
細胞分子医学研究室は、
体が
研究室は
遺伝学・生化学・インフォマティクスを
Key terms
- エピジェネティクス
- DNAの
配列は 変えずに、 DNAや それを 巻きつける タンパク質への 目印で 遺伝子の オン・ オフを 決める しく み - ポリコム群
- 発生に
かかわる 遺伝子のは たらきを 抑えて おくタンパク質の 集まり。 いく つかの 複合体を つくっては たらく - DNAメチル化
- DNAの
一部に 小さな 目印（メチル基）が 付く こと。 付いた 場所の 遺伝子は 読まれに くくなる - NKT細胞
- 免疫細胞の
一種。 がん細胞を 攻撃したり、 ほかの 免疫細胞を 呼び起こしたりする
NewsLab news
iPS-NKT細胞を
使う 新しい 細胞療法の 効果を、 医学研究院と 共同で 確認 iPS-NKT細胞を
頭頸部がんに 投与する 医師主導治験の 結果を、 千葉大学病院と 発表 ポリコム複合体の
分解に よる 転写活性化の しくみを 解明 （Molecular Cell） アトピー性皮膚炎の
バイオマーカーを、 慶應義塾大学などと 共同で 発見
ResearchResearch themes
エピジェネティックな
*Illustrative imageポリコム群がDNAに集まるしくみ
ポリコム群は
*Illustrative imageDNAメチル化を保つしくみ
メチル化された
*Illustrative imageDNA複製のタイミングの制御
遺伝子を
*Illustrative imageiPS細胞によるがん免疫治療
横浜事業所の
MembersFaculty
細胞分子医学研究室
- Professor古関 明彦
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Molecular Biology Laboratory, reflections - geograph.org.uk - 3763234” John Sutton / CC BY-SA 2.0 (cropped)
- ポリコム群が
DNAに 集まる しく み: “DNA-RNA-Protein-complex” Tyler Savitski / CC BY-SA 4.0 (cropped) - DNAメチル化を
保つしく み: “DNA methylation” Christoph Bock, Max Planck Institute for Informatics / CC BY-SA 3.0 (cropped) - DNA複製の
タイミングの 制御: “XBio illustration – DNA Replication Fork” explorebiology / CC BY 4.0 (cropped) - iPS細胞に
よるがん免疫治療: “A cell culture plate with induced pluripotent stem cells ( )” National Center for Advancing Translational Sciences from Bethesda, MD / Public domain (cropped) - Related lab (免疫細胞医学): “Лаборант готовит индивидуальный иммунологический препарат против рака из крови пациента” Иоанна Чернова / CC BY 4.0 (cropped)
- Related lab (イノベーション再生医学): “Hematopoietic Stem Cell (NIH BioArt 200)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (免疫発生学): “Immunology and Regenerative Medicine Research Laboratory - University of Calcutta - Ballygunge - Kolkata” Biswarup Ganguly / CC BY 3.0 (cropped)
- Related lab (血液内科学): “Connective Tissue Human Blood Leukocyte Survey ( )” Berkshire Community College Bioscience Image Library / CC0 (cropped)
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