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分子腫瘍学
Showing the original Japanese · View translation
ゲノムに付いた目印の異常から、がんの成り立ちに迫る研究室。

AboutAbout the lab
環境がエピゲノムを変え、がんを生む。
分子腫瘍学は、
同じ
感染や
がんの
Key terms
- エピゲノム
- DNAの
塩基配列その ものではなく、 そこに 付く 修飾の 情報。 どの 遺伝子を 使うかを 決める - DNAメチル化
- DNAの
決まった 場所に メチル基が 付く 修飾。 ふつうは その 領域の 働きを 止める - ヒストン修飾
- DNAを
巻き付ける タンパク質ヒストンに 付く 目印。 遺伝子を 働かせるか 止めるかに 関わる
NewsLab news
慢性
活動性EBV感染症の クロマチン異常に 関する 共同研究が Blood 誌に 掲載 博士課程で
進めた 頭頸部がんの 遺伝子メチル化の 研究が Cancer Science 誌に 掲載 HBV感染肝細胞の
クロマチン構造の 研究成果が Scientific Reports 誌に 掲載 臼井特任助教の
胃癌発症リスク管理に 関する 総説が Cancer Science 誌に 掲載 大学院生が、
KSBMB International Conference で Best Research Award を 受賞
ResearchResearch themes
エピゲノムとは、
*Illustrative image臨床標本のエピゲノム解析
がんの
*Illustrative image環境モデルで見るエピゲノム
次世代シーケンサーを
*Illustrative imageエピゲノム関連因子の機能
修飾を
*Illustrative imageエピゲノム異常と発症リスク
正常な
MembersFaculty
分子腫瘍学の
- Professor金田 篤志
- Project Associate Professor上田 宏生
- Project Lecturer中川 拓也
- Project Lecturer高根 希世子
- Assistant Professor福世 真樹
- Assistant Professor杉浦 正洋
- Project Assistant Professor関 元昭
- Project Assistant Professor臼井 源紀
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “ABI PRISM 3100 Genetic Analyzer 2” Mark Pellegrini / CC BY-SA 3.0 (cropped)
- 臨床標本の
エピゲノム解析: “Pipette gallery” User:Squidonius, myself, and User:Beliason (assumed). / CC BY-SA 4.0 (cropped) - 環境モデルで
見るエピゲノム: “Next Gen Sequencer (NIH BioArt 386)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped) - エピゲノム関連因子の
機能: “Nucleosome core particle 1EQZ v.5” Darekk2 using the cited above Protein Data Bank (PDB) structural data / CC BY-SA 3.0 (cropped) - エピゲノム異常と
発症リスク: “Checking Blood Sample ( )” National Eye Institute / CC BY 2.0 (cropped) - Related lab (先端データ医科学): “Illumina Hiseq 2000 sequencers, BGI Hong Kong sequencing room” Scotted400 / CC BY 3.0 (cropped)
- Related lab (次世代災害治療学): “Cryo-EM structure of the human nucleosome Histone H3.3 8KB5” Hirai S, Kujirai T, Akatsu M, Ogasawara M, Ehara H, Sekine SI, Ohkawa Y, Takizawa Y, Kurumizaka H / CC0 (cropped)
- Related lab (病原細菌制御学): “Escherichia coli O157-H7 CDC ID-10071” CDC / Janice Haney Carr / Public domain (cropped)
- Related lab (機能ゲノム学): “3a6p xpo5 ran miRNA” Opabinia regalis / CC BY-SA 3.0 (cropped)
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