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Ophthalmology Lab
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A lab investigating the mechanisms of eye inflammation and retinal diseases through six groups.
AboutAbout the lab
Ophthalmology built on three pillars: clinical care, education, and research
The ophthalmology lab studies how eye diseases arise at the cellular and molecular levels.
Research is carried out in six groups: ocular immunology, retinal cell biology (vascular and neural), ocular oncology and pathology, corneal cell biology, and ocular circulation and metabolism.
In the lab's Ocular Cell Biology and Visual Science Lab, faculty and graduate students work on experiments together.
Besides research using animal models, the lab analyzes tissue collected during surgery and uses AI to analyze images.
Key terms
- Uveitis
- A disease in which inflammation occurs in structures inside the eye such as the iris and choroid. Causes vary, and Behçet's disease is one of them.
- Retinal pigment epithelium
- The layer of cells at the outermost part of the retina that supports the photoreceptors, which receive light.
- Müller cells
- Glial cells in the retina that support the function and nutrition of neurons.
NewsLab news
The lab's orthoptist received the FY2026 Academic Encouragement Award from the Japanese Society for Ocular Inflammation
A graduate student received the Frate Research Encouragement Award from the Hokkaido University School of Medicine Alumni Association
A graduate student received the Bronze Award (Outstanding Presentation Encouragement Award) at the 29th Ophthalmic Molecular Biology Research Meeting
A physician of the lab received the Fukuda Award (Academic Encouragement Award) at the 20th Annual Meeting of the Japanese Society of Diabetic Ophthalmology
A graduate student received the Outstanding Presentation Award at the 41st Annual Meeting of the Japanese Society of Ocular Circulation
ResearchResearch themes
The lab aims to uncover the causes of eye diseases and lead to new treatments. Research is divided into six areas: inflammation, retinal blood vessels and nerves, tumors, the cornea, and ocular blood flow.
*Illustrative imageEye inflammation (ocular immunology)
Using uveitis model animals, the lab examines the effects of candidate new drugs. It also analyzes DNA and oral bacteria from the saliva of patients with Behçet's disease and examines their relationship to systemic conditions.
*Illustrative imageRetinal blood vessels and disease
The lab studies how a substance called acrolein affects vascular cells in diabetic retinopathy. It is also studying, in retinal pigment epithelial cells, the action of molecules common to age-related macular degeneration and Parkinson's disease.
*Illustrative imageProtecting retinal neurons
To find new glaucoma drugs, the lab studies mechanisms that protect retinal ganglion cells. Based on the hypothesis that retinal Müller cells are involved in clearing waste products, it focuses on the neuroprotective effects of eye drops.
*Illustrative imageEye tumors and pathology
The lab examines eye tumors and proliferative tissue collected during surgery by histopathology. It studies how conjunctival MALT lymphoma proliferates and how Müller cells escape cell death in diabetic retinopathy.
MembersFaculty
The lab's members consist of faculty, staff physicians and residents, graduate students, orthoptists, and secretaries, technical assistants, and physician clerks. Physicians from the Department of Ophthalmology at Hokkaido University Hospital also help supervise.As of 2026
- ProfessorSusumu Ishida
- Associate ProfessorKenichi Namba
- Clinical Associate ProfessorRyo Ando
- LecturerMichiyuki Saito
- Clinical LecturerRiki Kijima
- Clinical LecturerZhenyu Dong
- Clinical LecturerYoshiaki Tagawa
- Assistant ProfessorMiyuki Murata
- Assistant ProfessorKanae Fukutsu
- Project Assistant ProfessorKeitaro Hase
- Project Assistant ProfessorKayo Suzuki
- Assistant ProfessorYuka Mizukado
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Fundus photograph-normal retina EDA06” 作者不詳 / Public domain (cropped)
- Eye inflammation (ocular immunology): “Vascularised posterior synechia” Maria Sieglinda von Nudeldorf / CC BY-SA 4.0 (cropped)
- Retinal blood vessels and disease: “Fundus Proliferative retinopathy EDA01” 作者不詳 / Public domain (cropped)
- Protecting retinal neurons: “OCT Cross section retina scan” Bobjgalindo / CC BY-SA 4.0 (cropped)
- Eye tumors and pathology: “Marginal zone lymphoma - kidney -- high mag” Librepath / CC BY-SA 3.0 (cropped)
- Related lab (Neurosurgery Lab): “Circle of Willis - MRI, MIP - Anterior projection” Ceccomaster / CC BY-SA 3.0 (cropped)
- Related lab (Gastroenterology Lab): “Endoscopy” Linda Bartlett / Public domain (cropped)
- Related lab (Neurology Lab): “Neurological tools” Ali Raheem / CC BY-SA 3.0 (cropped)
- Related lab (Respiratory Medicine Lab): “Normal lateral chest radiograph (X-ray)” Mikael Häggström / CC0 (cropped)
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