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Gastroenterology Lab
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The lab studies the diagnosis and treatment of digestive diseases, from the liver and gastrointestinal tract to the biliary tract and pancreas.
AboutAbout the lab
A comprehensive gastroenterology department at the forefront of clinical care and research
The lab studies the diagnosis and treatment of diseases of the digestive organs, including the liver, gastrointestinal tract, biliary tract, and pancreas.
It has five specialty groups (liver, endoscopy, chemotherapy, biliary-pancreatic, and inflammatory bowel disease), and each group is engaged in clinical care and research.
From the perspective of clinicians, the lab places emphasis on clarifying how diseases arise, developing new treatments, and generating new clinical evidence.
In graduate school, each student works on a research topic together with a supervisor and writes it up as an original paper.
Key terms
- MASLD
- Metabolic dysfunction-associated steatotic liver disease. A condition in which fat accumulates in the liver along with metabolic abnormalities, and an increasing cause of liver cancer
- Clinical evidence
- The basis for diagnosis and treatment that has been confirmed by studies of patients
- Photoimmunotherapy
- A treatment that destroys cancer cells by shining light on a drug that binds to them
NewsLab news
Paper accepted to Endoscopy E-Videos
Paper accepted to Clinical and Experimental Hepatology
Paper accepted to International Journal of Clinical Oncology
Paper accepted to Hepatology Research
Paper accepted to ACG Case Reports Journal
ResearchResearch themes
Five specialty groups conduct research on diseases of the liver, gastrointestinal tract, biliary tract, and pancreas. There are many collaborations across faculties, and the work covers a broad range from basic research to clinical research.
*Illustrative imageLiver diseases
The lab conducts clinical and basic research on liver cancer, viral hepatitis, MASLD, and cirrhosis. MASLD is positioned as the top-priority research theme, and the lab studies noninvasive diagnostic methods using ultrasound and MR elastography as well as genetic research.
*Illustrative imageGastrointestinal endoscopy
The lab conducts clinical research on gastrointestinal endoscopy from the esophagus to the colon, and basic research that may lead to future diagnosis and treatment. Questions and insights that arise in daily clinical practice are the starting point of this research.
*Illustrative imageDrug therapy for digestive cancers
The lab conducts clinical research on drug therapy for esophageal, gastric, colorectal, and pancreatic cancers and GIST, through the planning and conduct of clinical trials. A colorectal cancer treatment developed mainly by the group has been included in the colorectal cancer treatment guidelines.
*Illustrative imageBiliary and pancreatic diseases
The lab conducts studies such as a multicenter clinical trial comparing biliary stents used during treatment of pancreatic cancer. It also works on a diagnostic method using duodenal fluid, jointly with the Department of Legal Medicine, and on photoimmunotherapy for pancreatobiliary cancer in cooperation with the Faculty of Pharmaceutical Sciences and the Institute for Genetic Medicine.
MembersFaculty
The lab's members consist of faculty, hospital staff physicians, graduate students, residents in specialty training, and visiting faculty and researchers. The faculty includes physicians affiliated with the Division of Endoscopy and the Cancer Center at Hokkaido University Hospital. Faculty from the Faculty of Pharmaceutical Sciences also join the lab.As of 2026
- ProfessorNaoya Sakamoto
- Professor, Department of EndoscopyShoko Ono
- Associate ProfessorYoshito Komatsu
- LecturerMasaki Kuwatani
- LecturerGoki Suda
- Assistant ProfessorTakehiko Katsurada
- Assistant ProfessorKazumichi Kawakubo
- Assistant ProfessorTakuya Syo
- Assistant ProfessorMasato Nakai
- Assistant ProfessorMasayoshi Ono
- Assistant ProfessorKazuaki Harada
- Assistant ProfessorKentaro Sawada
- Assistant ProfessorMasatsugu Ohara
- Project Assistant ProfessorRyo Sugiura
- Assistant ProfessorMasaki Inoe
- Assistant ProfessorShinsuke Odagiri
- Assistant ProfessorTakashi Kitagataya
- Professor, Faculty of Pharmaceutical SciencesSyunsuke Ohnishi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Endoscopy” Linda Bartlett / Public domain (cropped)
- Liver diseases: “Liver (254 13)” Doc. RNDr. Josef Reischig, CSc. / CC BY-SA 3.0 (cropped)
- Gastrointestinal endoscopy: “Colonoscopy splenic flexure” melvil / CC BY-SA 4.0 (cropped)
- Drug therapy for digestive cancers: “Poorly differentiated gastric adenocarcinoma, low mag.2” CoRus13 / CC BY-SA 4.0 (cropped)
- Biliary and pancreatic diseases: “Endosonographiegerät” Guntau / CC BY-SA 3.0 (cropped)
- Related lab (Dermatology Lab): “Skin section” Pathologist without beard / CC BY 4.0 (cropped)
- Related lab (Respiratory Medicine Lab): “Normal lateral chest radiograph (X-ray)” Mikael Häggström / CC0 (cropped)
- Related lab (Cardiovascular Medicine Lab): “Dresden, Deutsches Hygiene-Museum, anatomisches Modell, Herz” Dguendel / CC BY 4.0 (cropped)
- Related lab (Gastroenterological Surgery I Lab): “3D printed liver model - tumor” Jan Witowski / CC BY-SA 4.0 (cropped)
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