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Respiratory Medicine Lab
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The lab studies respiratory diseases, from asthma and COPD to lung cancer, through both clinical and basic research.
AboutAbout the lab
Deep specialization and whole-patient care, together
The lab studies a wide range of respiratory diseases, including lung cancer, interstitial pneumonia, pulmonary hypertension, respiratory infections, bronchial asthma, and COPD.
The lab places importance on resolving questions that arise in clinical practice through research, and it links clinical research with basic research.
The lab is divided into two groups, non-oncology and oncology, and in lung cancer it is also advancing the development of molecular targeted therapy and immunotherapy.
Students can take part in research activities even while they are still undergraduates.
Key terms
- COPD
- Chronic obstructive pulmonary disease. A disease in which the lungs and airways are damaged, making it hard to breathe out
- Interstitial pneumonia
- A disease in which inflammation occurs in the walls of the air sacs (alveoli) of the lungs, and the lungs gradually become stiff
- Cohort study
- A study that follows a group of people over a long period to examine the course of a disease and the factors related to it
ResearchResearch themes
The lab seeks to clarify the pathology of COPD, bronchial asthma, interstitial pneumonia, pulmonary hypertension, sarcoidosis, and respiratory infections through both clinical and basic research. In lung cancer, it aims to develop molecular targeted therapy and immunotherapy and to build new treatment strategies grounded in basic research.
*Illustrative imageLong-term follow-up studies of asthma and COPD
The lab conducts cohort studies that follow patients with COPD or refractory bronchial asthma over a long period. It also studies the condition in which asthma and COPD overlap, and image analysis of the airways and emphysema using 3D-CT is another pillar of its work.
*Illustrative imagePulmonary hypertension and interstitial pneumonia
In collaboration with three medical universities in Hokkaido, the lab has been conducting a prospective study of pulmonary hypertension and interstitial lung disease (the POPLAR study) since 2023. The study aims for more accurate assessment of the disease and for better treatment outcomes and prognosis.
*Illustrative imageClinical research on sarcoidosis
This research concerns sarcoidosis, an intractable disease whose cause is still unknown. The lab carries out nationwide epidemiological studies and, together with the Faculty of Veterinary Medicine, analyzes the bacterial microbiota in bronchoalveolar lavage fluid. It has also started a registry covering organs throughout the body.
*Illustrative imageResearch on respiratory infections
The lab participates as the clinical division of the Hokkaido University Institute for Vaccine Research and Development. Its main themes are nontuberculous mycobacterial infection and tuberculosis, and it also works with other universities on the clinical application of bacteriophage therapy.
MembersFaculty
The lab's staff consists of faculty of the Faculty of Medicine and physicians of the Department of Respiratory Medicine at Hokkaido University Hospital, and physicians from the hospital's clinical departments also join in supervising students and residents.As of 2026
- ProfessorSatoshi Konno
- ProfessorYasuyuki Nasuhara
- Project ProfessorIchizo Tsujino
- Professor, Regional Medical Cooperation and Welfare CenterJun Sakakibara
- Associate ProfessorHouman Goudarzi
- LecturerKaoruko Shimizu
- LecturerTakahiro Sato
- LecturerHirokazu Kimura
- Project Assistant ProfessorYasumoto Ikezawa
- Assistant ProfessorHidenori Kitai
- Assistant ProfessorKeisuke Kamada
- Assistant ProfessorYuta Tkashima
- Assistant ProfessorSho Nakakubo
- Project Assistant ProfessorMegumi Furuta
- Assistant ProfessorTetsuaki Shoji
- Assistant ProfessorJunichi Nakamura
- Project Assistant ProfessorKosuke Tsuji
- Assistant ProfessorDaisuke Morinaga
- Assistant ProfessorGaku Yamamoto
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Normal lateral chest radiograph (X-ray)” Mikael Häggström / CC0 (cropped)
- Long-term follow-up studies of asthma and COPD: “Emphysema, centrilobular ( )” Yale Rosen from USA / CC BY-SA 2.0 (cropped)
- Pulmonary hypertension and interstitial pneumonia: “UIP (Usual interstitial pneumonia)-Honeycomb fibrosis 3” Yale Rosen / CC BY-SA 2.0 (cropped)
- Clinical research on sarcoidosis: “Sarcoidosis histology skin involvement” Jensflorian / CC BY-SA 4.0 (cropped)
- Research on respiratory infections: “Mycobacterium tuberculosis Bacteria ( )” NIAID / CC BY 2.0 (cropped)
- Related lab (Respiratory and Circulatory Innovative Research Lab): “CTA Chest With Massive Pulmonary Embolism and Complete Occlusion” Rvahudson / CC BY-SA 4.0 (cropped)
- Related lab (Gastroenterology Lab): “Endoscopy” Linda Bartlett / Public domain (cropped)
- Related lab (Hematology Lab): “Red White Blood cells” Electron Microscopy Facility at The National Cancer Institute at Frederick (NCI-Frederick) / Public domain (cropped)
- Related lab (Neurosurgery Lab): “Circle of Willis - MRI, MIP - Anterior projection” Ceccomaster / CC BY-SA 3.0 (cropped)
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