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実験免疫学（Experimental Immunology）
Showing the original Japanese · View translation
制御性T細胞から免疫が自分に反応しない仕組みを探る研究室。
AboutAbout the lab
自分に反応しない免疫の仕組みを探る。
実験免疫学研究室は、
この
研究室は、
関節リウマチに
Key terms
- 制御性T細胞
- 自分の
組織と 反応する リンパ球の 活性化や 増殖を 抑える、 T細胞の 一群。 Treg細胞とも 呼ばれる - 免疫自己寛容
- 免疫の
仕組みが、 正常な 自分の 組織には 反応しない 状態。 自己免疫病では これが 崩れる - Foxp3
- 制御性T細胞が
生まれ、 働く ために 中心と なる マスター制御遺伝子 - エピゲノム
- DNAの
塩基配列その ものとは 別に、 遺伝子の 使われ方を 決める DNAメチル化などの 目印の 全体
NewsLab news
坂口志文特任教授が、
ノーベル生理学・医学賞を 受賞 坂口志文特任教授が、
米国免疫学会の 卓越フェローに 選出 共同研究で、
iTregの 分化・ 安定性・機能を 強化する 方法を 発見 （Nature） 共同研究で、
制御性T細胞を 安定化させる タンパク質を 発見 （Immunity） CD4+T細胞の
自己免疫疾患に おける 細胞応答が 明らかに （Cell Gen.）
ResearchResearch themes
この
*Illustrative image内在性制御性T細胞と免疫寛容
正常な
*Illustrative image関節リウマチとSKGマウス
研究室で
*Illustrative image制御性T細胞が生まれる仕組み
制御性T細胞の
MembersFaculty
実験免疫学研究室の
- Project Professor坂口 志文
- Project Professor大倉 永也
- Associate Professor市山 健司
- Associate Professor田中 淳
- Associate Professor三上 統久
- Associate Professor竹島 雄介
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Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to 実験免疫学（Experimental Immunology）
ヒト単一細胞免疫学
免疫化学
組織感染免疫学
免疫寄生虫学The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “HIV H9 T-cell II” National Institutes of Health (NIH) / Public domain (cropped)
- 内在性制御性T細胞と
免疫寛容: “T Regulatory Cells ( )” NIAID / CC BY 2.0 (cropped) - 関節リウマチと
SKGマウス: “Osteoarthritis and rheumatoid arthritis - Rheumatoid arthritis -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped) - 制御性T細胞が
生まれる 仕組み: “FOXP3” AtikaAtikawa / CC BY-SA 4.0 (cropped) - Related lab (ヒト単一細胞免疫学
（Human Single Cell Immunology） ): “Lymph Node (NIH BioArt 304)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped) - Related lab (免疫化学
（Immunochemistry） ): “Westgate Microscopy t-lymphocytes” Cannons Law Firm, Glasgow, UK / CC BY 4.0 (cropped) - Related lab (組織感染免疫学
（Tissue Immunology of Infection） ): “Infectiology - Herpes virus 1 -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped) - Related lab (免疫寄生虫学
（Immunoparasitology） ): “Toxoplasma parasites (tachyzoites) in a fibroblast host cell” Morne Arin (Ksena Longrin, previously known as Kseniia Bondarenko) / CC BY 4.0 (cropped)
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