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44 labs · 0 student voices
Faculties at The University of Osaka ›
Takeharu Nagai, Distinguished Professor
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The Biomolecular Science lab studies fluorescent proteins, bioluminescent proteins, microscopy, and related topics. According to the lab's website, it conducts research that only becomes possible by integrating optics, engineering, physics, chemistry, cell biology, developmental biology, botany, bioengineering, pharmaceutical sciences, and more. The lab accepts graduate students from the Graduate School of Pharmaceutical Sciences and the Graduate School of Frontier Biosciences at Osaka University. On the lab's website, it is introduced under the name "Nagai Lab" as the Biomolecular Function Science research division of the Institute of Scientific and Industrial Research.
Masahito Ikawa, Professor
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The Gene Function Analysis Lab studies reproductive biology at the whole-animal level, while developing tools to investigate gene function using reproductive engineering and developmental engineering. Genetically modified animals, whose genes have been artificially manipulated, now play an important role in disease research and basic biological research. On fertilization, the lab uses knockout mice and transgenic mice to re-examine long-held views. The lab carries out its research in collaboration with the Animal Resource Center for Infectious Diseases and others, and also supports the production of genetically modified animals through the NPO Developmental Engineering Research Society.
Yasuo Yoshioka, Project Professor
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The Nanodesign for Drug Discovery Lab aims to develop vaccines that people of all ages and genders can receive safely and with confidence, from pharmaceutical sciences perspectives such as drug delivery and safety science and toxicology. The lab is developing vaccines against a range of infectious diseases, including influenza virus, enterovirus, and cytomegalovirus, such as mRNA vaccines and intranasal vaccines. Working in close partnership with the Research Foundation for Microbial Diseases of Osaka University (BIKEN), the lab aims to seriously create the vaccines of ten years from now. On the lab's website it is introduced under the name "Vaccine Creation Group (Yoshioka Lab)," and in graduate school it is a cooperating research field of the Graduate School of Pharmaceutical Sciences.
Shota Nakamura, Professor
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The Nakamura Lab (Infectious Disease Metagenomics) conducts research aimed at understanding infectious diseases through genome analysis and metagenomic analysis of pathogens using next-generation sequencers. A metagenome is a concept that treats the genomes derived from a community of organisms living in an environment as a single aggregate. The lab also studies human commensal microbes, especially the gut microbiota, and conducts structural biology research on how pathogens colonize the intestinal tract. The lab belongs to the Bioinformatics Center of the Research Institute for Microbial Diseases.
Hirotaka Ie, Professor
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The Comprehensive Analysis Center plays a part in the wide range of materials research, from basic to applied, at the Institute of Scientific and Industrial Research, carrying out comprehensive compositional analysis and structural analysis of various materials. Large and medium-sized analytical instruments and computer systems that are widely shared among users are managed together, mainly in the Annex of the Research Building, and are maintained so that compositional analysis, structural analysis, and evaluation of physical properties can be carried out efficiently. Research projects using these instruments are also carried out, and the research introduction lists the development of asymmetric synthesis reactions and catalytic oxidation reactions.
Shinobu Takizawa, Professor
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The Precision Molecular Creation Chemistry Division (Takizawa Lab) studies the development of synthetic reaction processes with a small environmental burden, using energy from sunlight and electricity. To make reactions proceed efficiently and quickly, the lab also works on data-driven domino synthesis, which actively uses machine learning. Recently, in flow reaction processes using organocatalysts, the lab has used methods such as Bayesian optimization to find suitable reaction conditions in a short time from a minimal amount of training data. The lab is pioneering practical data-driven flow and electrochemical synthesis methods, aiming to reduce labor and improve productivity in precision organic synthetic chemistry.
Masaharu Iwasaki, Project Associate Professor
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The Division of Infectious Disease Drug Discovery Science studies emerging viral infectious diseases as the Iwasaki Lab of the Research Institute for Microbial Diseases. It focuses in particular on Lassa virus, which has a high fatality rate and for which there are no established treatments or preventive methods. Using methods from virology, immunology, molecular biology, RNA biology, bioinformatics, and chemical biology, the lab aims to elucidate how viruses replicate and how they cause disease. Based on the findings, the lab also works on developing new diagnostic methods, treatments, and preventive methods.
Yasunori Shintani, Director
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The Department of Molecular Pharmacology searches for molecules that can serve as therapeutic targets and aims to create new treatments, with the goal of conquering cardiovascular disease. Using methods from biochemistry, pharmacology, genetics, molecular biology, structural biology, and computational chemistry, the lab investigates how target molecules function and how that function breaks down in disease. Its main research subjects are the respiratory chain enzymes of mitochondria and membrane proteins involved in inflammation of the heart muscle. The lab's website is presented under the name "Department of Molecular Pharmacology" at the Research Institute, National Cerebral and Cardiovascular Center.
Shigemiki Omiya, Director
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The Department of Heart Failure Pathophysiology and Control aims to clarify the pathophysiology of heart failure, find new therapeutic targets, and develop effective treatments. Heart failure has a high prevalence and a poor prognosis, so developing effective treatments is considered urgent. Focusing on cardiomyocyte death, autophagy, and sterile inflammation, the lab investigates molecular mechanisms mainly in mouse models of heart failure. The lab's website presents it under the name "Department of Heart Failure Pathophysiology and Control."
Jun Kunisawa, Visiting Professor
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The lab conducts basic immunology research focusing on the unique features of mucosal immunity, and applies the findings to the development of mucosal vaccines and immunotherapies. Inhaled and oral mucosal vaccines have been put into practical use for some infectious diseases, but extending them to other infectious diseases and allergies requires the development of vaccine materials. The lab's website is presented as the "Vaccine Materials Project" of the National Institutes of Biomedical Innovation, Health and Nutrition. Students of the Graduate School of Pharmaceutical Sciences at Osaka University also join the lab as affiliated graduate students.
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