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Basic Medical Science of Pathogen Response Lab
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The lab investigates how viruses use cells to multiply and cause disease.
AboutAbout the lab
To understand viruses, understand host cells too.
Unlike bacteria and fungi, viruses cannot multiply without using the functions of host cells.
The Basic Medical Science of Pathogen Response Lab (Ibuki Lab) studies the relationship between how viruses replicate and host cell functions, aiming to elucidate how viral infections arise.
Currently, the lab focuses on the replication mechanisms and pathogenicity of mosquito-borne viruses and HIV.
To curb the spread of infectious diseases, the lab also aims to develop new testing methods that are simple, sensitive, and accurate.
Key terms
- Host
- An organism or cell that a virus or parasite enters and uses as a place to live and multiply.
- HIV
- Human immunodeficiency virus. It causes AIDS.
- Mosquito-borne virus
- A virus transmitted through mosquito bites, such as dengue virus and Zika virus.
- Extracellular vesicle
- A small sac released by a cell. It encloses substances and carries information to other cells.
ResearchResearch themes
To understand the relationship between viral pathogenicity and host cell functions, the lab works on the following themes.
*Illustrative imageMosquito-borne viral infections
The lab studies mosquito-borne viruses such as dengue virus, chikungunya virus, and Zika virus.
*Illustrative imagePrimate immunodeficiency viruses
Using an experimental system based on simianized mice, the lab investigates the mechanisms by which viruses cause disease and the immune mechanisms that protect the body effectively.
*Illustrative imagePlant-derived extracellular vesicles
The lab studies the effects of plant-derived extracellular vesicles on the human immune system and on microbial growth, as well as the mechanisms behind them.
MembersFaculty
- Associate ProfessorKentaro Ibuki
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “An Aedes Mosquito and Dengue, Zika, and Chikungunya Viruses” NIAID / CC BY 2.0 (cropped)
- Mosquito-borne viral infections: “Aedes Mosquito and Dengue Virus Particles” NIAID / CC BY 2.0 (cropped)
- Primate immunodeficiency viruses: “HIV-infected T cell ( )” NIAID / CC BY 2.0 (cropped)
- Plant-derived extracellular vesicles: “Canadian Pond Weed Leaf Tip” KarlGaff / CC BY 4.0 (cropped)
- Related lab (Developmental Neurobiology Lab): “The developing cerebral cortex” Shyam K Akula , David Exposito-Alonso , Christopher A Walsh / CC BY 4.0 (cropped)
- Related lab (Glycobiology Lab): “Glycan” Guennadi Kozlov, Kalle Gehring / CC BY-SA 4.0 (cropped)
- Related lab (Cancer Occupational Therapy Lab): “Cancer Survivors Garden Pavilion” RUmtz15470 / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Research and Development Lab): “Follicular lymphoma -- low mag” Nephron / CC BY-SA 3.0 (cropped)
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