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分子生物学【生化学第一】
Showing the original Japanese · View translation
がんの治療標的と、ゲノムを守る仕組みを探る研究室。
AboutAbout the lab
分子の仕組みから、がんの治療法を探る。
島田研究室は、
乳がんや
プロリン異性化が
医学科3年生は
Key terms
- エストロゲン受容体
- 女性ホルモンの
エストロゲンと 結合する 受容体 （ERα）。 陽性の 乳がんでは、 働きを 抑える 内分泌療法を 行う - カルシニューリン
- カルシウムシグナルを
仲介する 脱リン酸化酵素。 免疫抑制剤FK506の 標的分子 - プロリン異性化
- プロリンの
直前の ペプチド結合が、 シス型と トランス型で 切り 替わる 変化。 立体構造の 変化に つながる
NewsLab news
View More ↗ResearchResearch themes
遺伝情報の
*Illustrative image難治性がんの治療標的と治療戦略
乳がん細胞では
*Illustrative imageプロリン異性化と生命現象
プロリン異性化酵素は、
*Illustrative imageカルシウムシグナルの異常とがん
カルシニューリンが
*Illustrative imageヒストンのリン酸化と遺伝子の転写
Chk1と
MembersFaculty
島田研究室の
- Professor島田 緑
- Assistant Professor坪田 庄真
- Assistant Professor榊原 正太郎
- Assistant Professor杉山 成明
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Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to 分子生物学【生化学第一】
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泌尿器科学医学部 医学科前立腺癌、The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Smartphone colorimetry – 96-well microplate with serial dilutions of coloured solutions” Mdc-science / CC BY-SA 4.0 (cropped)
- 難治性がんの
治療標的と 治療戦略: “Invasive Breast Cancer in 3D” Sshah74 / CC BY 4.0 (cropped) - プロリン異性化と
生命現象: “Alpha fold model for DmBCA - Drosophila melanogaster” AlphaFold Data Copyright (2021) DeepMind Technologies Limited. Jumper, J et al. Highly accurate protein structure prediction with AlphaFold. Nature (2021). Varadi, M et al. AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models. Nucleic Acids Research (2021). / CC BY 4.0 (cropped) - カルシウムシグナルの
異常と がん: “Crystal structure of the CavAb voltage-gated calcium channel(wild-type, 2.7A)” Tang, L., Gamal EL-Din, T.M., Swanson, T.M., Pryde, D.C., Scheuer, T., Zheng, N., Catterall, W.A. / CC BY-SA 4.0 (cropped) - ヒストンの
リン酸化と 遺伝子の 転写: “Cryo-EM structure of the human nucleosome Histone H4 8KB5” Hirai S, Kujirai T, Akatsu M, Ogasawara M, Ehara H, Sekine SI, Ohkawa Y, Takizawa Y, Kurumizaka H / CC0 (cropped) - Related lab (分子細胞薬理学【薬理学】): “Microscope à fluorescence (Ifremer )” Olivier Dugornay / CC BY 4.0 (cropped)
- Related lab (分子細胞化学【生化学第二】): “Biochemistry Lab - Tirunelveli Medical College” Kallidaimaniac (talk) / Public domain (cropped)
- Related lab (分子細胞免疫学【免疫学】): “Immunology and Regenerative Medicine Research Laboratory - University of Calcutta - Ballygunge - Kolkata” Biswarup Ganguly / CC BY 3.0 (cropped)
- Related lab (泌尿器科学): “Operating-room 2” 연세건우병원 / CC BY 4.0 (cropped)
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