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Noguchi Lab
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The lab explores molecular targets for drug discovery in viral infections and virus-associated cancers.
AboutAbout the lab
Finding molecular targets of viral infections for next-generation drug discovery
The Noguchi Lab conducts basic research on molecular targets for drug discovery in viral infections and virus-associated cancers.
Its research field is the study of molecular targets in infectious diseases.
The lab aims to identify new molecular targets for urgent emerging and re-emerging viral infections and cancer-related infectious diseases, and to contribute to next-generation drug discovery.
In its research on emerging and re-emerging viral infections, the lab advances basic virology research in collaboration with the National Institute of Infectious Diseases and the National Institute of Health Sciences.
Key terms
- Molecular targets for drug discovery
- Molecules that drugs act on. The process by which viruses multiply also contains such targets.
- Emerging and re-emerging viral infections
- Emerging infections are those caused by new pathogens; re-emerging infections are those in which a known pathogen spreads again.
- Latent infection
- A state in which a virus infects a cell while stably maintaining its genome inside it.
NewsLab news
A student won a Poster Award at the 38th Microbiology Symposium
A paper on joint research with the Faculty of Pharmacy, Keio University, was published in Journal of Molecular Biology
A student received an Outstanding Student Presentation Award at the 146th Annual Meeting of the Pharmaceutical Society of Japan
ResearchResearch themes
The lab conducts basic research to find new molecular targets for drugs in viral infections and virus-associated cancers. It aims to identify molecular targets for urgent emerging and re-emerging viral infections and cancer-related infectious diseases, and to contribute to next-generation drug discovery.
*Illustrative imageSearching for targets in emerging and re-emerging viral infections
In emerging and re-emerging infections such as COVID-19, the lab treats the process by which the virus multiplies as a target for drug discovery. In collaboration with the National Institute of Infectious Diseases and the National Institute of Health Sciences, it aims to search for inhibitors.
*Illustrative imageMolecular target research on virus-associated cancers
The lab has studied, as molecular targets for treatment, the mechanisms by which Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) maintain their genomes in cells during latent infection. It is currently analyzing how virus-derived molecules in infected cells are involved in the expression of immune checkpoint molecules, and aims to search for inhibitors of them.
MembersFaculty
The members of the Noguchi Lab are faculty, a visiting professor, master's and undergraduate students, and alumni.As of 2026
- ProfessorKohji Noguchi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Human Respiratory Syncytial Virus (RSV) ( )” NIAID / CC BY 2.0 (cropped)
- Searching for targets in emerging and re-emerging viral infections: “Usutu Virus model, its gene structure, and the proteins encoded by its genome - Viruses-07-00219-g002” Ashraf, Usama; Ye, Jing; Ruan, Xindi; Wan, Shengfeng; Zhu, Bibo; Cao, Shengbo / CC BY 4.0 (cropped)
- Molecular target research on virus-associated cancers: “Papilloma Virus (HPV) EM” Author: Unknown photographer/artist Source: Laboratory of Tumor Virus Biology / Public domain (cropped)
- Related lab (佐藤(聡)研究室): “Clear cell renal cell carcinoma -- intermed mag” Nephron / CC BY-SA 3.0 (cropped)
- Related lab (吉澤研究室): “Hospital room ubt” Tomasz Sienicki [user: tsca, mail: tomasz.sienicki at gmail.com] / Public domain (cropped)
- Related lab (礒濱研究室): “Blausen 0620 Lungs NormalvsInflamedAirway” BruceBlaus. When using this image in external sources it can be cited as: Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN . / CC BY 3.0 (cropped)
- Related lab (髙澤研究室): “Purine Nucleoside Phosphorylase” 作者不詳 / Public domain (cropped)
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