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Respiratory Medicine Lab
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The lab aims to overcome respiratory diseases such as asthma, COPD, and lung cancer.

AboutAbout the lab
Valuing “why” in the pursuit of overcoming respiratory diseases.
The Respiratory Medicine Lab conducts a broad range of research, from basic to clinical, with the goal of overcoming all respiratory diseases.
The main research targets are bronchial asthma, chronic obstructive pulmonary disease (COPD), interstitial pneumonia, lung cancer, and infectious diseases such as nontuberculous mycobacterial disease.
It is a clinical department of the University of Tsukuba Hospital, with clinical care, education, and research as its pillars.
In graduate school, the lab recruits graduate students and research students for the doctoral program of the Major in Disease Control Medicine, Graduate School of Comprehensive Human Sciences.
Key terms
- Chronic obstructive pulmonary disease
- A lung disease also called COPD. The airways narrow, making it hard to breathe
- Interstitial pneumonia
- A disease in which inflammation occurs in the part that forms the walls of the lungs. As it progresses, it can lead to pulmonary fibrosis, in which the lungs become stiff
- Immune checkpoint inhibitor
- A drug that releases the brakes on the immune system's activity, helping it attack cancer cells
NewsLab news
A doctor in the department received the Excellent Presentation Award at the 13th Kanto Regional Meeting of the Japanese Society of Allergology
Lecturer Masashi Matsuyama received the Imamura Award at the Japanese Society for Tuberculosis and Nontuberculous Mycobacterial Diseases
Hospital Lecturer Kazufumi Yoshida received the Sanofi Excellent Paper Award from the Japanese Society of Allergology
ResearchResearch themes
Respiratory diseases are diverse, and for most of them adequate treatment has not been established. The lab conducts a broad range of research, from basic to clinical, with the goal of overcoming all respiratory diseases.
*Illustrative imagePathophysiology of bronchial asthma and factors that make it refractory
The lab investigates the pathophysiology and genetic factors of bronchial asthma. It explores the factors that determine response to biologics in severe asthma and the factors that make asthma refractory to treatment, and also works on developing new treatments that target them.
*Illustrative imagePathophysiology and treatment of chronic obstructive pulmonary disease
The lab investigates the pathophysiology and genetic factors of chronic obstructive pulmonary disease. It also works on developing treatments that target transcription factors.
*Illustrative imagePathophysiology of interstitial pneumonia and acute lung injury
The lab investigates the pathophysiology of interstitial pneumonia/pulmonary fibrosis and of acute lung injury (ALI/ARDS).
*Illustrative imageEffects and prognosis of drug therapy for lung cancer
The lab conducts multicenter surveys, observational studies, and retrospective analyses within Ibaraki Prefecture on drug therapy for advanced non-small cell lung cancer and extensive-stage small cell lung cancer. This includes prognostic factors of treatment combining chemotherapy with immune checkpoint inhibitors, and verification of prednisolone therapy for immune-related lung injury.
MembersFaculty
The members of the Respiratory Medicine Lab consist of faculty members.
- Associate ProfessorYuko Morishima
- LecturerTakumi Kiwamoto
- LecturerHironori Masuko
- LecturerToshihiro Shiozawa
- LecturerMasashi Matsuyama
- Hospital LecturerKazufumi Yoshida
- Hospital LecturerHaruna Kitazawa
- Hospital LecturerKai Yazaki
- Hospital LecturerChio Sakai
- LecturerTetsushi Ano
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Chest x-ray plain film normal” Ptrump16 / CC BY-SA 4.0 (cropped)
- Pathophysiology of bronchial asthma and factors that make it refractory: “Peak flow meter horiz” No machine-readable author provided. Tomhannen assumed (based on copyright claims). / Public domain (cropped)
- Pathophysiology and treatment of chronic obstructive pulmonary disease: “Chest X-ray” Ptrump16 / CC BY-SA 4.0 (cropped)
- Pathophysiology of interstitial pneumonia and acute lung injury: “HRCT Chest Scan Showing COVID-19 Lung Infection (Ground-Glass Opacities)” Goleisureintl / CC BY 4.0 (cropped)
- Effects and prognosis of drug therapy for lung cancer: “Chemotherapy vials (1)” Bill Branson (Photographer) / Public domain (cropped)
- Related lab (Nephrology Lab): “Hemodialysis equipment” U3061292 / CC BY-SA 3.0 (cropped)
- Related lab (Clinical Oncology Lab): “Oncology ward” Lovelyn Obiakor / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Pharmacy Lab): “Pills and medicines 02” BuhaM / CC BY-SA 4.0 (cropped)
- Related lab (Hematology Lab): “Eosinophil blood smear” Bobjgalindo / CC BY-SA 4.0 (cropped)
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