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Disaster Infectious Diseases Lab (International Research Institute of Disaster Science)
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The lab studies how to control infectious diseases in disasters, including through antiviral drugs.
AboutAbout the lab
Tackling infectious diseases in disasters with antiviral drugs
The lab focuses on infectious diseases in disasters and studies the development of antiviral drugs and other treatments for infectious diseases.
It works not only on the epidemiology and diagnosis of pathogens but also on developing therapeutic drugs, and it also clarifies the mechanisms of drug resistance and improves diagnostic methods.
International collaborative research with the United States and other countries, as well as within Japan, is active.
The lab belongs to the Disaster Medical Science Division of the International Research Institute of Disaster Science, and its faculty also hold appointments in the Graduate School of Medicine.
Key terms
- Antiviral drug
- A drug that treats viral infections by suppressing the replication of viruses.
- Drug resistance
- When a virus changes so that a drug that previously worked becomes less effective.
- Combination drug
- A drug that combines multiple active ingredients into one.
ResearchResearch themes
Infectious diseases that occur in disasters are highly diverse, so it is more realistic to respond according to transmission routes and symptoms than pathogen by pathogen. The lab studies infection control methods, diagnostic methods for viruses, and the development of therapeutic drugs such as antiviral drugs.
*Illustrative imageInfection control in disasters
In disasters, it is more realistic to respond to infectious diseases according to transmission routes, such as airborne and contact transmission, and symptoms, rather than pathogen by pathogen. The lab aims to establish infection control methods for disaster settings.
*Illustrative imageRapid and simple virus diagnosis
The lab is working to develop and establish rapid and simple methods for diagnosing viruses.
*Illustrative imageDevelopment of anti-HIV drugs
An HIV integrase inhibitor developed jointly with Japan Tobacco has been approved as a combination drug in the United States and Japan. The lab was also involved in the basic development of an HIV reverse transcriptase inhibitor that is effective not only for treatment but also for preventing infection. The description of this item on the website dates from around 2016.
*Illustrative imageTreatment for EB virus-associated leukemia
The lab is jointly developing a treatment for EB virus-associated leukemia with Tokyo Medical and Dental University and the National Center for Child Health and Development. It is particularly effective against chronic active EBV infection.
MembersFaculty
- ProfessorEiichi Kodama
- Assistant ProfessorHironori Hayashi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Airmen conduct emergency medical response exercise (8750214)” U.S. Air Force 380AEW by Senior Airman Sir Wyrick / Public domain (cropped)
- Infection control in disasters: “Hand wash” PhoToria / CC BY-SA 4.0 (cropped)
- Rapid and simple virus diagnosis: “Corona positive Rapid Antigen test ( )” dronepicr / CC BY 2.0 (cropped)
- Development of anti-HIV drugs: “HIV (human immunodeficiency virus) (NIH BioArt 659)” NIH NIAID Ryan Kissinger / Public domain (cropped)
- Treatment for EB virus-associated leukemia: “Epstein Barr Virus (NIH BioArt 144)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (Global Health Policy Lab (International Research Institute of Disaster Science)): “World map of HIV prevalence, 2023” Our world in data / CC BY 4.0 (cropped)
- Related lab (Microbiology Lab): “Colorized transmission electron micrograph of rabies virus particles (green) image captured at the NIAID Integrated Research Facility in Fort Detrick, Maryland - 9” NIAID / CC BY 2.0 (cropped)
- Related lab (Environmental Medicine Lab): “Disposable Pipette Tips in Laboratory Tip Boxes 02” Gannu03 / CC BY-SA 4.0 (cropped)
- Related lab (Redox Molecular Medicine Lab): “Liquid chromatograph with mass spectrometer, in CAFIA laboratory, Czech Republic” Sarka Na kopci / CC BY-SA 4.0 (cropped)
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