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Clinical Physiological Testing Lab
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A lab that studies physiological tests such as electrocardiography, from basic research through to clinical practice.
AboutAbout the lab
Using tests as a window to understand disease.
The Clinical Physiological Testing Lab studies clinical physiological tests such as electrocardiography, echocardiography, and pulmonary function testing, viewing them as important "windows" into how diseases develop.
The lab pursues basic research, clinical research, and the work of making new technologies usable in clinical settings as one integrated effort.
Basic experiments investigating the mechanisms of right heart failure and large-scale clinical studies are the two pillars of the lab.
Going forward, the lab also aims to incorporate technologies such as AI into clinical research and to envision a new role for clinical laboratory technologists, with task shifting in healthcare settings in mind.
Key terms
- Clinical physiological tests
- Tests that examine how the body functions, such as electrocardiography, echocardiography, and pulmonary function testing
- Right heart failure
- A condition in which the right side of the heart weakens and has difficulty pumping blood to the lungs
- Registry
- A database that collects and accumulates information on patients from many institutions
ResearchResearch themes
Viewing clinical physiological tests as a window into disease, the lab investigates how diseases arise through both basic experiments and clinical research. It also incorporates AI-based data analysis to advance understanding of heart and lung diseases.
*Illustrative imageBasic experiments on the mechanisms of right heart failure
Focusing on mitochondrial function and calcium handling, the lab conducts basic experiments to uncover how stress is placed on the right heart and how right heart failure develops.
*Illustrative imageLarge-scale clinical studies
The lab leads the nationwide pulmonary hypertension registry (the JAPHR study) and the CHECKHEART-BC study in cardio-oncology. Its work includes verifying the effects of new drugs on prognosis, developing scores to predict cardiotoxicity, and data mining and image analysis using AI.
MembersFaculty
- ProfessorKoichiro Sugimura
- LecturerHaruka Sato
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “NABL Accredited Clinical Pathology Laboratory in Kharghar Navi Mumbai Diagnostic Services” Goleisureintl / CC BY 4.0 (cropped)
- Basic experiments on the mechanisms of right heart failure: “Molecular Cell Biology Laboratory - LUMC” mararie from Leiden, The Netherlands / CC BY-SA 2.0 (cropped)
- Large-scale clinical studies: “2D ECHOCARDIOGRAM MACHINE WITH A TABLE AND A STETHOSCOPE” Dr D. Malleswara Rao / CC BY-SA 4.0 (cropped)
- Related lab (病理検査学): “Histologic Slide under MIcroscope” Ed Uthman from Houston, TX, USA / CC BY-SA 2.0 (cropped)
- Related lab (画像診断学): “TORNAI-SpectrumOfMedicalImaging” Martin Tornai / CC BY 4.0 (cropped)
- Related lab (分子内分泌学): “Polyacrylamide gel electrophoresis of Proteins” Jean-Etienne Minh-Duy Poirrier from Bruxelles, Belgium / CC BY-SA 2.0 (cropped)
- Related lab (医用画像工学): “Computed Tomography (CT) Scan Facility in Navi Mumbai” Goleisureintl / CC BY 4.0 (cropped)
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