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Obstetrics and Fetal Pathophysiology Lab
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A lab that unravels the mysteries of the intrauterine environment during pregnancy, aiming at new diagnosis and treatment.
AboutAbout the lab
To protect mothers and the tiniest lives
The Department of Obstetrics and Fetal Pathophysiology aims to unravel the mysteries of the intrauterine environment during pregnancy, create new knowledge, and develop entirely new methods of diagnosis and treatment.
The lab covers research from basic to clinical, working on artificial placentas and artificial wombs, fetal electrocardiography, and basic research in mice.
In its predecessor, the Department of Biomedical Engineering for Fusion of Medicine and Engineering, the lab put great effort into developing fetal electrocardiography, which records the electrical signals of the fetal heart through the mother's abdominal wall, and succeeded in bringing it to market as a product.
The lab's website lists side by side the names of Obstetrics and Fetal Pathophysiology in the Graduate School of Medicine and Near-Future Life Information Engineering in the Graduate School of Biomedical Engineering.
Key terms
- Fetal electrocardiography
- A recording of the electrical signals of the fetal heart, taken through the mother's abdominal wall
- Preterm birth
- Delivery between 22 and 36 weeks of pregnancy
- DOHaD
- The concept that environmental factors during the embryonic period, the fetal period, and early after birth affect future health and the risk of developing diseases
NewsLab news
Paper by Prof. Kasahara published in The Journal of Nutrition
Paper by a graduate of the lab published in IEEE Access
Paper by a graduate of the lab published in Scientific Reports
ResearchResearch themes
The lab aims to unravel the mysteries of the intrauterine environment during pregnancy and to develop new methods of diagnosis and treatment. It works on artificial placentas and artificial wombs, fetal electrocardiography, and basic research in mice.
*Illustrative imageArtificial womb and artificial placenta systems
A major research theme of Prof. Saito is the artificial womb and artificial placenta system. Japan's perinatal care outcomes are among the best in the world, but the preterm birth rate remains high, and this trend is expected to continue as the age of mothers at childbirth rises.
*Illustrative imageChallenges in managing and treating preterm birth
Preterm birth is increasing worldwide, and saving preterm infants is an important challenge for perinatal care in a society with a low birth rate and an aging population. Reliable methods for managing and treating threatened preterm labor have not yet been established, and they are not standardized across countries.
*Illustrative imageThe fetal environment and future health
Events that reach the fetus through the mother during the embryonic period, the fetal period, and early after birth can affect a baby's future health and susceptibility to disease. This concept is called DOHaD.
MembersFaculty
The members of the lab consist of faculty, professors emeritus, technical staff, secretaries, and technical assistants.As of 2026
- ProfessorMasatoshi Saito
- Associate ProfessorYoshiyuki Kasahara
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Fetal Anomaly Ultrasound Scan in Navi Mumbai” Goleisureintl / CC BY 4.0 (cropped)
- Artificial womb and artificial placenta systems: “UTI Neonatal - Hospital Mário Dourado Sobrinho - Irecê - BA” Manu Dias / AGECOM / CC BY 2.0 (cropped)
- Challenges in managing and treating preterm birth: “Mother with premature baby in incubator” PublicDomainPictures / CC0 (cropped)
- The fetal environment and future health: “Pregnant woman holds white babygrow sleeper” Petr Kratochvil (https://publicdomainpictures.net/en/browse-author.php?a=1) / CC0 (cropped)
- Related lab (Perinatal Medicine Lab): “Mcmaster premie NICU 7045” Peter K Burian / CC BY-SA 4.0 (cropped)
- Related lab (Molecular Epidemiology Lab (Environment and Genome Research Center)): “Edward & Cynthia Institute of Public Health ( ECIPH) MPH Scholars after a field visit in Mangalore” Ginevrajocosa88 / CC0 (cropped)
- Related lab (Medical Biochemistry Lab): “Pipette de laboratoire sur fond blanc au Bénin 03” Adoscam / CC BY-SA 4.0 (cropped)
- Related lab (Psychosomatic Medicine Lab): “FMRI coronal scan of Nathanial Bradford” Nathanial Luceus / CC BY 2.0 (cropped)
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