LAB LOGA page on LabLog, a review site (not the lab's official page)
Blood Regeneration and Regulation Lab
Machine-translated · View original
A lab that explores how platelets are produced in the bone marrow, with the aim of creating bone marrow in culture.
AboutAbout the lab
Understanding bone marrow, and building it.
The Blood Regeneration and Regulation Lab studies how blood cells, especially platelets, are produced in the bone marrow.
The lab focuses on megakaryocytes, the cells that give rise to platelets, and on the bone marrow environment that surrounds them.
It also works on developing bone marrow organoids, which recreate bone marrow through cell culture, and on genetic analysis of hereditary blood coagulation disorders.
Key terms
- Megakaryocyte
- A cell that differentiates from a hematopoietic stem cell in the bone marrow. It produces platelets, which are responsible for stopping bleeding
- Microenvironment
- The local environment formed by other cells and proteins immediately surrounding a cell. It influences the differentiation and maturation of blood cells
- Organoid
- A small organ-like tissue made by culturing cells. It is expected to serve as a tool for studying development and disease and for regenerative medicine
NewsLab news
A doctoral student received the Clinical Laboratory Technologist Excellent Presentation Award at the 47th Annual Meeting of the Japanese Society on Thrombosis and Hemostasis
A factor that controls the differentiation of megakaryocyte subtypes was discovered and published in Thrombosis Research
A master's student received the Excellent Presentation Award at the General Meeting of the Hokkaido Branch of the Japanese Society of Laboratory Medicine
A master's student received the Best Poster Award at the Hokkaido University Cross-Departmental Symposium
A master's student received the Clinical Laboratory Technologist Excellent Presentation Award at the 46th Annual Meeting of the Japanese Society on Thrombosis and Hemostasis
ResearchResearch themes
The lab aims to clarify how platelets are produced in the bone marrow and what in the bone marrow environment regulates this, and to advance toward understanding diseases and toward regenerative medicine. It also works on creating bone marrow in culture and on analyzing hereditary blood coagulation disorders.
*Illustrative imageThe bone marrow environment that produces platelets
Platelets are produced in the bone marrow from cells called megakaryocytes. Focusing on cells called PDPN-positive stromal cells, the lab investigates how the bone marrow microenvironment that regulates megakaryocyte blood cell production is formed and maintained.
*Illustrative imageDevelopment of bone marrow organoids
The lab is working to clarify how bone marrow develops and how the environment that supports blood cell production is formed, and to recreate it in culture to make bone marrow organoids. These are expected to lead to models of blood diseases and materials for regenerative medicine.
*Illustrative imageHereditary blood coagulation disorders
The lab analyzes the genes of hereditary diseases such as those in which bleeding does not stop easily or blood clots form easily, and investigates at the cellular level why the changes it finds cause disease. This is joint research with institutions including Nagoya University Hospital.
MembersFaculty
The Blood Regeneration and Regulation Lab consists of faculty members and doctoral, master's, and undergraduate students.As of 2025
- Associate ProfessorShogo Tamura
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Blood Regeneration and Regulation Lab
Senkenji LabSchool of Medicine, Department of Health SciencesPathological cell biology, regenerative medicine, and rehabi…
Kamishima LabSchool of Medicine, Department of Health SciencesDiagnostic radiology; musculoskeletal radiology (imaging dia…
Cellular Metabolic Chemistry LabSchool of Medicine, Department of Health SciencesClinical chemistry, analytical chemistry, health science, li…
Adaptive Exercise Medical Science LabSchool of Medicine, Department of Health SciencesFundamental physical therapy, neuroscience (neuromodulation …The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Megakaryocyte” Simon Caulton / CC BY-SA 3.0 (cropped)
- The bone marrow environment that produces platelets: “Megakaryocyte in bone marrow” Animalculist / CC BY-SA 4.0 (cropped)
- Development of bone marrow organoids: “SI organoid 1” Abhimanu.pandey / CC BY 4.0 (cropped)
- Hereditary blood coagulation disorders: “3D render of a human blood clot formed in vitro under flow” Joanne Mitchell / CC BY-SA 4.0 (cropped)
- Related lab (Senkenji Lab): “MSCs D21” MFT29 / CC BY-SA 4.0 (cropped)
- Related lab (Kamishima Lab): “Knee MRI T1 TSE Sagittal” Ptrump16 / CC BY-SA 4.0 (cropped)
- Related lab (Cellular Metabolic Chemistry Lab): “Adipocytes Lipid Droplets Oil Red O Staining Rkott 2023” Rkott / CC BY-SA 4.0 (cropped)
- Related lab (Adaptive Exercise Medical Science Lab): “Mouse running on a standard wheel” Manuelito2021consupadre / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.