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Molecular Microbiology and Infection Control Laboratory Science Lab
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A lab that works to clarify how bacteria interact with cells and with other microorganisms.

AboutAbout the lab
Unraveling how bacteria interact with cells and with other microbes.
Under the keyword "microbial interactions," the lab studies at the cellular and molecular levels how bacteria continue to infect cells.
Using primitive environmental chlamydiae that live inside amoebae, the lab investigates how pathogenic bacteria have adapted to humans.
The lab also studies how the pathogenic Chlamydia trachomatis multiplies inside infected cells.
Key terms
- Chlamydia
- A group of bacteria that can multiply only inside the cells of other living organisms. Some cause disease in humans, and others live inside amoebae
- Amoeba
- A single-celled organism that moves by changing its shape and lives by taking in bacteria and other organisms
- Co-culture
- Growing two or more kinds of organisms together in the same container
NewsLab news
A paper was accepted by Microbiology and Immunology
A master's student received an Excellent Presentation Award at the 99th General Meeting of the Japanese Society for Bacteriology
A paper was accepted by Next Research
A master's student received an Excellence Award at the 89th Scientific Meeting of the Hokkaido Branch of the Japanese Society for Bacteriology
A paper was accepted by Microbes and Environments
ResearchResearch themes
Under the keyword "microbial interactions," the lab investigates at the cellular and molecular levels how bacteria persistently infect cells. It also studies the interactions between bacteria and protozoa such as amoebae and ciliates.
*Illustrative imageAdaptive evolution explored through environmental chlamydiae
Pathogenic chlamydiae are thought to have lost many molecules as they adapted to human cells. Using primitive environmental chlamydiae that live inside amoebae, the lab aims to find these lost molecules and investigate their functions.
*Illustrative imageInteractions between microorganisms
The lab co-cultures Legionella, a cause of pneumonia, with amoebae, and E. coli, whose reduced susceptibility to drugs is a problem, with ciliates (Paramecium), and studies the interactions between microbes that arise from living together.
MembersFaculty
The members of the Molecular Microbiology and Infection Control Laboratory Science Lab consist of faculty, master's students, and fourth-year undergraduates doing their graduation research.As of 2025
- ProfessorHiroyuki Yamaguchi
- LecturerTorahiko Okubo
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “ChlamydiaTrachomatisEinschlusskörperchen” User Marcus007 on de.wikipedia / Public domain (cropped)
- Adaptive evolution explored through environmental chlamydiae: “Acanthamoeba polyphaga cyst” Photo Credit: Content Providers(s): CDC/ Dr. George Healy / Public domain (cropped)
- Interactions between microorganisms: “Paramecium caudatum Ehrenberg, 1833” Deuterostome / CC BY-SA 3.0 (cropped)
- Related lab (Environmental Health Sciences Lab): “Japanese living by Emile Bremmer is licensed under CC BY 2.0” Emile B from Europe / CC BY 2.0 (cropped)
- Related lab (Fukunaga Lab (Radiation Biology Lab)): “Mitochondria 7 -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
- Related lab (Biomedical Science and Engineering Lab): “Beta radiation in a cloud chamber” Nuledo / CC BY-SA 4.0 (cropped)
- Related lab (Pathological and Immunological Laboratory Science Lab): “Renal corpuscle” Ed Uthman (Pathologist) / CC BY-SA 2.0 (cropped)
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