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Fukunaga Lab (Radiation Biology Lab)
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A radiation biology lab that investigates how radiation affects reproduction and the next generation.
AboutAbout the lab
Pursuing radiation, the "double-edged sword."
The Fukunaga Lab studies the effects of radiation on human health from medical and biological perspectives.
Radiation is useful in medicine and other fields, but exposure also carries risks such as cancer, which is why it is called a "double-edged sword."
In particular, the lab examines the effects of radiation on reproduction and on the next generation, focusing on how they relate to the spatial distribution and timing of exposure.
The lab was established in April 2022 and is in charge of education for the Radiological Science and Technology Division and the Graduate School of Health Sciences.
Key terms
- Microbeam
- A very finely focused beam of radiation that can irradiate only a targeted spot
- Mitochondrial DNA
- A small piece of DNA held by the mitochondria inside cells, separate from the DNA in the cell nucleus
- Radiation protection
- The principles and systems for minimizing harm to people and the environment when radiation is used
NewsLab news
A paper by Professor Fukunaga and colleagues was published in Environment & Health
A paper by Professor Fukunaga and colleagues was published in the Japanese Journal of Health Physics (Hoken Butsuri)
A paper by Professor Fukunaga and colleagues was published in the International Journal of Molecular Sciences
A paper by Professor Fukunaga and colleagues was published in Physics in Medicine & Biology
A paper by Professor Fukunaga and colleagues was published in The Tohoku Journal of Experimental Medicine
ResearchResearch themes
Radiation can cause cancer in humans, yet it is essential for diagnosis and treatment. The lab investigates how these two effects arise, using microbeams, animal models, and large-scale cohort studies, with the aim of improving the safety of radiation use in medicine and strengthening the scientific basis of radiation protection.
*Illustrative imageSpatial distribution of exposure and tissue response
The lab studies how non-uniform irradiation of the body affects the mechanisms of sperm production, fertility, and tissue recovery. It uses microbeams, in vitro cultured testis models, and mice in which spermatogenesis can be tracked by luminescence.
*Illustrative imageMitochondrial responses across generations
The lab studies how radiation exposure before pregnancy or in the womb changes the amount, state, and regulation of mitochondrial DNA in parents and their children. The aim is to find clues that complement conventional assessments, which have focused mainly on genetic mutations in nuclear DNA.
*Illustrative imageRadiation protection and environmental and occupational health
Drawing on clinical and public health experience after the Fukushima Daiichi nuclear power plant accident, the lab investigates radiation risk at the individual and population levels. It also studies how scientific evidence can be used to protect health and to communicate information clearly.
MembersFaculty
- ProfessorHisanori Fukunaga
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Mitochondria 7 -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
- Spatial distribution of exposure and tissue response: “Seminiferous tubule and sperm” Nephron / CC BY-SA 3.0 (cropped)
- Mitochondrial responses across generations: “Mitochondria in living HeLa cells” 8x57is / CC BY-SA 4.0 (cropped)
- Radiation protection and environmental and occupational health: “Geiger counter dosimeter measuring radiation (cropped)” Kiwiev / CC0 (cropped)
- Related lab (Environmental Health Sciences Lab): “Japanese living by Emile Bremmer is licensed under CC BY 2.0” Emile B from Europe / CC BY 2.0 (cropped)
- Related lab (Human Ecology Lab): “Mukuni Village, Zambia ( )” Ninara / CC BY 2.0 (cropped)
- Related lab (Kamishima Lab): “Knee MRI T1 TSE Sagittal” Ptrump16 / CC BY-SA 4.0 (cropped)
- Related lab (Community Health Nursing/Public Health Nursing Lab): “Sapporo City Skyline” ノボホショコロトソ / CC BY 4.0 (cropped)
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