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反応創薬化学分野
Showing the original Japanese · View translation
新しい分子と反応を生み出し、創薬につなげる研究室。
AboutAbout the lab
分子を自在に設計・合成し、新しい反応と分子を生み出す。
反応創薬化学分野は、
グループでは、
化学・薬学の
学部
Key terms
- タンパク質間相互作用（PPI）
- タンパク質どうしが
結合して 働く 仕組み。 多くの 生命現象を 制御し、 創薬の 標的と される - 重水素化医薬品
- 水素原子を
重水素に 置き換えた 医薬品。 重水素には 代謝速度を 抑える 効果が ある - ラジカル反応
- 一般に
反応が 速く立体障害の 影響を 受けに くい。 アニオン・ カチオン反応では 難しい 構造の 構築にも 適する
NewsLab news
重水素化に
関する 総説が、 Tetrahedron Chem 誌に 掲載 論文が、
Organic Letters 誌に 掲載 論文が、
Nature Catalysis 誌に 掲載 （産総研、 名古屋工業大学との 共同研究） 論文が、
Nature Communications 誌に 公開（名古屋工業大学との 共同研究） 分子合成薬学講座と
反応創薬化学分野が 発足
ResearchResearch themes
反応創薬化学分野と
*Illustrative imageオリジナル分子を活用した創薬研究
独自に
ラジカルを活用した反応開発
炭素ラジカルや
MembersFaculty
分子合成薬学講座と
- Lecturer大澤 歩
- Associate Professor矢崎 亮
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薬物分子設計学分野薬学部 創薬科学科・臨床薬学科擬天然物化学・擬複合糖質(高機能型アナログ分子)の
蛋白質創薬学分野薬学部 創薬科学科・臨床薬学科蛋白質科学／疾患にThe information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Fume hood and table of elements, early XX century Gdansk University of Technology” LukaszKatlewa / CC BY 4.0 (cropped)
- オリジナル分子を
活用した 創薬研究: “Biological Target Prediction of Bioactive Molecules Based on Minimum Structures Identification” SSamadi15 / CC BY-SA 4.0 (cropped) - Related lab (環境調和創薬化学分野): “Palladium on carbon” Marbletan / CC0 (cropped)
- Related lab (精密分子変換化学分野): “Positron Emission Tomography” Christkannada / CC BY-SA 4.0 (cropped)
- Related lab (薬物分子設計学分野): “Kandiszucker” Dietmar Rabich / CC BY-SA 4.0 (cropped)
- Related lab (蛋白質創薬学分野): “Structural basis for inhibition of TSLP-signaling by Tezepelumab” Kvrstra / CC BY-SA 4.0 (cropped)
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