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Protein Drug Discovery Lab
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The lab aims to discover drugs by using protein interactions as a starting point.
AboutAbout the lab
Understanding and controlling disease-related proteins
The Protein Drug Discovery Lab studies interactions between biomolecules, with the aim of understanding and controlling proteins involved in disease.
Using advanced measurement techniques, the lab examines interactions involved in cancer, inflammatory diseases, infectious diseases, and more.
It develops small molecules, peptides, and antibodies that can control these interactions, and also aims to design new drug modalities using protein engineering.
Structural analysis, which determines the structures of target proteins by NMR, X-ray crystallography, and cryo-electron microscopy, is the central pillar of the lab's research.
Key terms
- Drug modality
- The type or format of a molecule used as a drug. Typical examples are small molecules, peptides, and antibodies.
- X-ray crystallography
- A method for determining the three-dimensional shape of a molecule by shining X-rays on a crystal of a protein.
- Cryo-electron microscopy
- A method for determining the shape of a molecule by observing a frozen sample with an electron microscope.
NewsLab news
An Assistant Professor and a master's student won the Outstanding Poster Presentation Award at the Regulatory Science Forum
A master's student was selected for the Excellence Award at the training camp of the Kyushu Pharmaceutical Science Research and Education Consortium
A doctoral student won the Outstanding Poster Presentation Award at the Summer School of the Young Researchers' Group of the Division of Biofunctional Chemistry
A master's student won a Poster Award at the Annual Meeting of the Protein Science Society of Japan
An Assistant Professor received the Young Researcher Encouragement Award and a master's student received a Poster Award at the Annual Meeting of the Protein Science Society of Japan
ResearchResearch themes
The lab deepens understanding of interactions between biomolecules involved in cancer, inflammatory diseases, infectious diseases, and more, and develops molecules that can control those interactions. In addition to small molecules, peptides, and antibodies, it aims to design new drug modalities using protein engineering.
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MembersFaculty
The members of the Protein Drug Discovery Lab consist of faculty members, a secretary, and doctoral, master's, and undergraduate students.As of 2026
- ProfessorCaaveiro Jose
- Assistant ProfessorAkinobu Senoo
- Assistant ProfessorKeisuke Kasahara
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Structural basis for inhibition of TSLP-signaling by Tezepelumab” Kvrstra / CC BY-SA 4.0 (cropped)
- Seeing the shape of target proteins through structural analysis: “Protein structure examples” Axel Griewel / CC BY-SA 3.0 (cropped)
- Related lab (グローバルファーマシー分野): “Florfenicol molecule ball” Jynto (more from this user) / CC0 (cropped)
- Related lab (薬理学分野): “Glial cells in the mouse spinal cord” xtream1101 (archive user) / CC BY-SA 4.0 (cropped)
- Related lab (創薬構造解析学分野): “Autism Aspect Pain Sensitivity 1” MissLunaRose12 / CC BY-SA 4.0 (cropped)
- Related lab (薬
物動態学分野): “Pharmacy, Medicine Store, DrugsBank” ManzoorRph / CC BY-SA 4.0 (cropped)
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