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分子創製学研究室（高木研）
Showing the original Japanese · View translation
シグナル伝達の仕組みを蛋白質の形から探る研究室。
AboutAbout the lab
蛋白質の「しくみ」を識り、新たな蛋白質を「創る」。
分子創製学研究室は、
大きなくくりでは
立体構造を
材料と
Key terms
- 構造生物学
- 蛋白質の
立体構造から、 それが 働くしくみを 調べる 学問分野 - シグナル伝達
- 細胞外の
分子 （リガンド）が 受容体に 結合して、 細胞に 情報を 伝える しく み - インテグリン
- 細胞が
細胞外マトリックスや他の 細胞に 接着する ときに、 その 仲立ちを する 受容体
NewsLab news
東北大学、
小野薬品工業などとの 共同研究の 論文が、 Cell Stem Cell 誌に 公開 大阪大学 医学系研究科との
共同研究の 論文が、 Nature Cancer 誌に 公開 がん特異的抗HER2抗体に
関する 論文が、 Structure 誌に 公開
ResearchResearch themes
この
*Illustrative imageセマフォリンのシグナル伝達
セマフォリンは、
*Illustrative imageWntシグナル伝達経路
Wntシグナル伝達経路は、
*Illustrative image細胞接着分子インテグリン
インテグリンは
*Illustrative imageがん進展にかかわるHGFとMet
肝細胞増殖因子HGFは
MembersFaculty
分子創製学研究室の
- Professor高木 淳一
- Associate Professor有森 貴夫
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Crystal structure of Sec23aSec24aSec22 complexed with a C-terminal II sorting motif - Protein transport protein Sec24A 5VNG” Ma W, Goldberg E, Goldberg J / CC0 (cropped)
- セマフォリンの
シグナル伝達: “Protein Structure of human NDNF” Alpha Fold Team / CC BY 4.0 (cropped) - Wntシグナル伝達経路: “Wnt-Signal CY-Lavoisier” The original uploader was Ycomb at French Wikipedia. / CC BY-SA 3.0 (cropped)
- 細胞接着分子インテグリン: “Substrate Adhesion Molecules” Innertuber40 / CC BY-SA 4.0 (cropped)
- がん進展に
かかわる HGFと Met: “PDB 3cth EBI” Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute / Public domain (cropped) - Related lab (機能構造計測学グループ): “900 MHz unshielded Oxford magnet Svenskt NMR centrum Gothenburg” Adville / CC BY-SA 4.0 (cropped)
- Related lab (スピン構造生物学研究室
（宮ノ入研） ): “NMR instrument” SamihaAlam1999 / CC BY-SA 4.0 (cropped) - Related lab (電子構造生物学研究室
（加藤研） ): “FEI Titan 50-300 PICO” ER-C, Forschungszentrum Jülich / CC BY-SA 4.0 (cropped) - Related lab (超分子構造解析学グループ): “National Synchrotron Light Source II Quadrupole Magnet Model” Henrysz / CC BY 4.0 (cropped)
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