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Spin Structural Biology Lab
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A lab that uses NMR to reveal the dynamic structures of proteins.
AboutAbout the lab
Investigating the dynamic structures of proteins with NMR.
The Spin Structural Biology Lab develops methods to analyze the dynamic structures of proteins, using nuclear magnetic resonance (NMR) spectroscopy and its own stable isotope labeling.
The lab aims to clarify the relationship between the structure and motion of proteins and their biological functions.
The lab is located in the Institute for Protein Research at Osaka University, and can accept graduate students from the Graduate School of Frontier Biosciences, and from the Departments of Biological Sciences and Chemistry in the Graduate School of Science.
Solution NMR is the main method, but the lab welcomes students of any background and hopes they will approach research from a variety of perspectives.
Key terms
- Nuclear magnetic resonance (NMR)
- A spectroscopic method that uses nuclear magnetic resonance. Research in this lab is mainly based on solution NMR
- Stable isotope labeling
- Labeling that uses stable isotopes. The lab has developed methods to analyze the dynamic structures of proteins using its own labeling
- Dynamic structure
- A view of a protein's structure that includes its motion, not only its static shape
ResearchResearch themes
The lab investigates protein function from the viewpoints of three-dimensional structure, modes of interaction, and dynamic changes. To clarify the relationship between structure, motion, and biological function, it uses nuclear magnetic resonance (NMR) spectroscopy.
View More ↗MembersFaculty
The members of the Spin Structural Biology Lab are faculty, project researchers, visiting faculty, and technical assistants.
- ProfessorYohei Miyanoiri
- Associate Professor (Concurrent)Yo Matsuki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “NMR instrument” SamihaAlam1999 / CC BY-SA 4.0 (cropped)
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