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129 labs · 0 student voices
Other departments in Faculty of Medicine ›Faculties at Tohoku University ›
Shunji Mugikura, Professor
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The Brain Imaging Survey Unit is in charge of additional MRI examinations and cognitive and psychological tests in the Tohoku Medical Megabank Project. It aims to clarify how constitution (genetic factors) and lifestyle affect the brain, cognitive function, and mental state. The unit conducts the "Brain and Mental Health Survey" with people who took part in the Three-Generation Cohort Study or the Community-Based Cohort Study and who want an MRI examination. From the survey results, it builds a large-scale brain imaging database, aiming to advance early diagnosis and prevention of conditions such as depression, PTSD, and dementia.
Mari Dezawa, Professor
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The Cell Histology Lab conducts research in regenerative medicine centered on Muse cells, a novel type of pluripotent stem cell. Muse cells are stem cells found in the mesenchymal tissues of adult humans that can differentiate into various types of cells, and they were discovered by this lab. Because these cells can be obtained from adults, are non-tumorigenic, and have a broad capacity for tissue repair, they are expected to be applied to a wide range of diseases. The lab works on both basic analysis and application to regenerative medicine.
Hozumi Motohashi, Professor
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The Medical Biochemistry Lab studies how redox (oxidation-reduction) metabolism in the body supports the regulation of gene function. It aims to understand the mechanisms by which living organisms respond to stress, adapt to their environment, and sustain life. The lab investigates the roles in the body of supersulfide molecules, recently discovered biomolecules, and seeks to clarify the basis of inflammation and cancer pathology. Overcoming intractable cancers with abnormally activated NRF2 is also one of the lab's central research aims.
Kei Takase, Professor
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The Diagnostic Radiology lab handles diagnostic imaging performed in the hospital, as well as IVR (interventional radiology, or image-guided treatment), in which thin needles or catheters are inserted into the body under image guidance to treat disease. Diagnostic radiologists also act as specialists who "read" (interpret) images obtained from CT, MRI, nuclear medicine, and PET examinations and make medical diagnoses. The lab has specialists by organ system, such as neuroradiology, chest, abdominal, and cardiovascular imaging, and by examination method, and it also works on the use of AI and on cutting-edge nuclear medicine research. On the lab's website, it is presented as the Department of Diagnostic Radiology at Tohoku University Hospital.
Koetsu Ogasawara, Professor
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The Biodefense Lab (Institute of Development, Aging and Cancer) studies the immune system in relation to cancer, autoimmune diseases, and infectious diseases caused by immune abnormalities that accompany aging. The lab focuses on how NK cells and T cells distinguish their target cells. Using animal models and genetic engineering techniques, the lab clarifies how diseases develop, with the aim of developing new diagnostics and treatments. The lab welcomes students from a wide range of backgrounds who are interested in its research.
Kei Igarashi, Professor (International Eminent)
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The Cognitive Physiology Lab (Igarashi Lab) studies where in the brain information received from the outside world is converted into control of intention (cognitive control). Focusing on a brain region called the lateral entorhinal cortex, the lab has studied how olfactory information is converted into memory information. Going a step beyond its previous memory research, the lab aims to move on to research on cognitive control, which gives rise to the mind. On the lab's website, it is introduced under the name "Igarashi Lab."
Yuji Oowada, Professor
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The Developmental Neuroscience Lab uses rats and mice to study how the mammalian brain is formed. The lab explores at the molecular level how the brain forms, develops, and is maintained. When small flaws enter these mechanisms, neurodevelopmental disorders such as autism spectrum disorder arise. The lab is also interested in how the large neocortex that leads to humans was acquired, and in how sex differences in the brain arise. The lab takes part in the Neuro Global International Joint Graduate Program, and has many international students.
Chiharu Ota, Professor
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The Developmental Environmental Medicine Lab studies how the environment during the fetal and neonatal periods affects the development and growth of children after birth. Based on the DOHaD hypothesis, the lab focuses on exposure to chemical substances such as secondhand smoke, to heavy metals, and to digital devices. The lab analyzes information collected through questionnaires and in-person surveys, using data from the Japan Environment and Children's Study (JECS), a birth cohort study run by the Ministry of the Environment since 2011. The lab also conducts joint research with clinical departments at Tohoku University Hospital and affiliated hospitals.
Masafumi Goto, Professor
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The Transplantation and Regenerative Medicine Lab focuses on pancreatic islet transplantation and hepatocyte transplantation as treatments for diabetes and liver disease. Islet transplantation is a minimally invasive cell therapy in which the pancreatic islets, which regulate blood glucose, are isolated from the pancreas and transplanted into the liver in a manner similar to an intravenous drip. The lab aims to establish a curative therapy for severe diabetes, including type 1 diabetes, which was previously considered incurable. Together with the staff who carry out clinical islet transplantation, the lab conducts translational research that bridges basic research and clinical practice.
Ko Matsui, Professor
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The Super-network Brain Physiology Lab (Matsui Lab) studies the question "What is the mind?" through signal transmission between cells in the brain. The brain contains glial cells in addition to neurons, and the lab investigates how signals are passed between neurons and glia. Through this, the lab aims to understand how mental functions arise. Using thin brain slices from mice and rats as well as living mice, the lab manipulates brain cell activity with light and electricity and measures the responses. The lab accepts graduate students from both the Graduate School of Life Sciences and the Graduate School of Medicine.
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