Labs in The University of Osaka, Immunology Frontier Research Center, Imaging Group

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1細胞1分子イメージング（Single Molecule Imaging）／柳田研 (introduction coming soon)

Single-molecule measurement and imaging of intracellular information-processing molecular systems using proteins as biological elements

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The lab observes how immune cells move inside the living body to understand how they work.

The Immunology and Cell Biology Lab studies how immune and blood cells move and function inside the body by observing them in living mice. Cells of the immune and blood systems circulate throughout the body and maintain functional links among organs. The lab aims to elucidate the basic principles by which this dynamic network maintains the integrity of organs and tissues. By visualizing the movements of the cells that break down bone and the cells that build it inside bone, the lab works to elucidate the mechanisms of diseases such as rheumatoid arthritis and osteoporosis and to develop new drugs. The lab can accept graduate students from both the Graduate School of Medicine and the Graduate School of Frontier Biosciences.

#In vivo imaging #Osteoclasts #Immune cell dynamics

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A chemical biology lab that uses fluorescence and MRI to visualize molecules and reactions inside living organisms.

The lab studies chemical biology: it uses molecules made with chemical methods to investigate how biomolecules function inside living cells and animals. It designs and synthesizes by organic synthesis molecules whose fluorescence intensity or color changes when they encounter biomolecules in the body, and molecules that change MRI contrast (probe molecules). As a bar for its research, the lab requires that the molecules it creates can actually be used in biological research. The core discipline is chemistry, but students also study biology and physics as needed.

#Chemical biology #Fluorescent probes #MRI probes

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A lab that investigates, at the cellular and molecular level, how the nervous system regulates immunity.

The lab aims to clarify, at the cellular and molecular level, how the nervous system controls the function of the immune system. Using mice, it investigates mechanisms such as how the sympathetic nervous system alters lymphocyte movement and creates day-night differences in immune responses. In addition, using molecules involved in lymphocyte migration as clues, the lab works on developing new treatments for autoimmune diseases. In January 2026, Prof. Suzuki took up a post at the Graduate School of Medicine (Environmental Response Pharmacology), and is moving the lab while holding a concurrent appointment at the Immunology Frontier Research Center (IFReC).

#Neural regulation of immunity #Sympathetic nerves #Autoimmune diseases

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A lab developing optical technologies that distinguish the state of immune cells without staining.

The lab develops new optical technologies that can be used to investigate problems in immunology and biology. Much of its research is on developing label-free techniques that examine immune-related information at the molecular, cellular, and tissue levels without staining or other markers. It is particularly interested in the changes that occur in cells when they receive immune stimulation. The lab collaborates with applied physics research groups at the University of Osaka, and also welcomes collaboration with researchers in physics, biology, and chemistry.

#Raman scattering #Label-free imaging #Immune cells

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The lab investigates how the brain experiences pain, combining computational models and experiments.

The Seymour Lab studies how the brain processes pain, using both theory and experiments. It treats pain as a signal that prompts behavior to protect the body, and uses computational models to study pain prediction and the learning of escape and avoidance. The lab conducts behavioral experiments and brain imaging studies in humans, and also aims to develop new technologies for treating pain. The lab's website is written as an introduction to a research group based at the University of Oxford.

#Pain #Reinforcement learning #fMRI