LAB LOGA page on LabLog, a review site (not the lab's official page)
Immune Response Dynamics Lab
Machine-translated · View original
A lab that investigates, at the cellular and molecular level, how the nervous system regulates immunity.
AboutAbout the lab
Uncovering the link between the nervous system and immunity
The lab aims to clarify, at the cellular and molecular level, how the nervous system controls the function of the immune system.
Using mice, it investigates mechanisms such as how the sympathetic nervous system alters lymphocyte movement and creates day-night differences in immune responses.
In addition, using molecules involved in lymphocyte migration as clues, the lab works on developing new treatments for autoimmune diseases.
In January 2026, Prof. Suzuki took up a post at the Graduate School of Medicine (Environmental Response Pharmacology), and is moving the lab while holding a concurrent appointment at the Immunology Frontier Research Center (IFReC).
Key terms
- Sympathetic nervous system
- Together with the parasympathetic nervous system, it forms the autonomic nervous system and coordinates the function of organs throughout the body.
- Chemokine receptor
- A receptor that governs the migration of immune cells. A type of G protein-coupled receptor.
- Autoimmune disease
- A disease in which the immune system turns against the body's own tissues and impairs their function. Rheumatoid arthritis is a typical example.
NewsLab news
A paper by an Assistant Professor and colleagues was published in The Journal of Clinical Investigation
Recruiting graduate students for admission in April 2027; visits are accepted at any time
A student won the top award at the Annual Meeting of the Japanese Society for Immunodeficiency and Autoinflammatory Diseases
An undergraduate medical student won the Best Presentation Award at the Basic Medical Science Lab Placement Research Presentation
ResearchResearch themes
How input from the nervous system affects the immune system, and the cellular and molecular mechanisms behind it, are not yet well understood. Aiming to clarify the cellular and molecular basis of immune regulation by the nervous system, the lab works on the link between nerves and immunity and on developing new drugs for immune diseases.
*Illustrative imageSympathetic nerve control of lymphocyte dynamics
Studies in mice showed that when sympathetic nerves release noradrenaline, lymphocytes stay in the lymph nodes. In mice, sympathetic nerve activity rises at night, and the number of lymphocytes in the lymph nodes increases. Immunization at night produced a stronger immune response than during the day.
*Illustrative imageDeveloping treatments that target lymphocyte migration
The lab found that the COMMD3/8 complex promotes chemokine receptor signaling. In mouse models of rheumatoid arthritis lacking this complex, the progression of arthritis was suppressed, and celastrol, a compound that inhibits the complex's function, suppressed it in the same way.
MembersFaculty
Members of the lab consist of faculty, visiting faculty, concurrent faculty, research students, doctoral and master's students, technical staff, and secretaries.As of 2026
- ProfessorKazuhiro Suzuki
- Assistant ProfessorTaiichiro Shirai
- Assistant ProfessorSatomi Komori
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Immune Response Dynamics Lab
Immunology and Cell Biology LabImmunology Frontier Research Center, Imaging GroupVisualization of immune cell dynamics by intravital live ima…
Chemical Imaging Techniques LabImmunology Frontier Research Center, Imaging GroupChemical biology; visualization of intracellular and in vivo…
Seymour LabImmunology Frontier Research Center, Imaging GroupPain information processing in the brain; regulation of beha…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “HIV-1 virus particles colorized scanning electron micrograph - 411” NIAID / CC BY 2.0 (cropped)
- Sympathetic nerve control of lymphocyte dynamics: “Lymph Node of Person Without HIV” NIAID / CC BY 2.0 (cropped)
- Developing treatments that target lymphocyte migration: “CCR5 chemokine receptor (molecular surface representation) with an illustration of a cell membrane in the background” NIAID / CC BY 2.0 (cropped)
- Related lab (Immunology and Cell Biology Lab): “Bone marrow embolus ( )” Yale Rosen from USA / CC BY-SA 2.0 (cropped)
- Related lab (Chemical Imaging Techniques Lab): “Fluorescence Imaging Experiment 01” Yurii Kandurov, Ksenia Kandurova, Dmitry Stavtsev / CC BY 4.0 (cropped)
- Related lab (Seymour Lab): “Stuttering-brain-scan-neurosciennews” DanaAlmutawaaa / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.