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Seymour Lab
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The lab investigates how the brain experiences pain, combining computational models and experiments.
AboutAbout the lab
Neuroscience of pain and aversive systems.
The Seymour Lab studies how the brain processes pain, using both theory and experiments.
It treats pain as a signal that prompts behavior to protect the body, and uses computational models to study pain prediction and the learning of escape and avoidance.
The lab conducts behavioral experiments and brain imaging studies in humans, and also aims to develop new technologies for treating pain.
The lab's website is written as an introduction to a research group based at the University of Oxford.
Key terms
- reinforcement learning
- A branch of control theory in which learning about the world happens through trial and error
- endogenous control
- The way the pain system regulates, from within, what a person feels
NewsLab news
View More ↗ResearchResearch themes
Many brain regions are known to respond to pain, but what is required for the conscious perception of pain is still not understood. This lab breaks pain down into several components and then reassembles them, exploring from an information-processing perspective the pathway through which subjective pain arises.
*Illustrative imageLearning to Predict and Avoid Pain
The lab views pain as a learning signal that also helps reduce future injury, and studies pain prediction and escape and avoidance using computational models. It considers reinforcement learning a key to understanding the computations the brain performs when it learns about pain.
*Illustrative imageModels of Pain Perception and Control
The lab treats pain perception as a process of inferring the causes of sensory stimuli, and proposes a model that works in stages, from simple reflexes in the spinal dorsal horn to conscious pain behavior in the brain. It holds that this interaction also appears in endogenous control.
*Illustrative imageFrom Basic Science to Clinical Application
The lab combines theoretical modeling with behavioral experiments and brain imaging studies in humans. Basic science is the core of its work, but it also pursues translational research on musculoskeletal pain, fatigue, and anxiety.
MembersFaculty
The Seymour Lab's members are faculty, postdoctoral researchers, and doctoral and master's students.
- ProfessorBen Seymour
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Stuttering-brain-scan-neurosciennews” DanaAlmutawaaa / CC BY-SA 4.0 (cropped)
- Learning to Predict and Avoid Pain: “Aprendizado por Reforço” Leomaurodesenv / CC0 (cropped)
- Models of Pain Perception and Control: “Nociception Illustration” Wiki coDü / CC BY-SA 4.0 (cropped)
- From Basic Science to Clinical Application: “XBio illustration – Functional Magnetic Resonance Imaging (fMRI)” explorebiology / CC BY 4.0 (cropped)
- Related lab (Biophotonics Lab): “AFM-Raman microscope” AAMonitor96 / CC BY-SA 3.0 (cropped)
- Related lab (Immune Response Dynamics Lab): “HIV-1 virus particles colorized scanning electron micrograph - 411” NIAID / CC BY 2.0 (cropped)
- Related lab (Immunology and Cell Biology Lab): “Bone marrow embolus ( )” Yale Rosen from USA / CC BY-SA 2.0 (cropped)
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