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51 labs · 0 student voices
Faculties at Hokkaido University ›
Takafumi Fujimoto, Professor
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The Developmental Biology Lab uses medaka and loach to study germ cells, the cells that give rise to sperm and eggs. The loach group led by Professor Takafumi Fujimoto and the medaka group led by Associate Professor Toshiya Nishimura work together to run the lab. Using medaka, a model fish species, and loach, a non-model species in which clonal reproduction has been found, the lab aims to clarify, at the gene level, reproductive mechanisms shared across species. The loach group also studies how genome composition affects gamete formation, and develops technologies that use germ cells to preserve and regenerate genetic resources.
Toshiki Uji, Associate Professor
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The Uji Lab studies the mechanisms of seaweed reproduction, focusing on laver (amanori) red algae, the raw material for nori. Seaweeds are thought to sense changes in their surrounding environment and regulate the switch from growth to reproduction, but the mechanism is still unknown. To enable sustainable seaweed production, the lab works to clarify reproductive mechanisms and to develop technologies that form the basis of breeding (variety improvement). The lab also studies the reproductive mechanisms of Gracilaria (ogonori), a red alga used as a raw material for agar.
Kazuki Sugawara, Assistant Professor
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Assistant Professor Kazuki Sugawara studies methods to sustainably increase and grow useful seaweeds, based on reproductive mechanisms and relationships between organisms. Seaweeds are highly diverse organisms, but most of them are still not well understood. The lab aims to understand seaweed diversity and reproduction, and to obtain basic knowledge that leads to techniques for seaweed bed restoration and aquaculture.
Akira Inoue, Professor
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Professor Akira Inoue's lab studies the genes and proteins of enzymes found in marine organisms. Marine organisms have many enzymes that terrestrial organisms do not. Focusing on enzymes such as those that break down polysaccharides, the lab uses methods including gene cloning, heterologous expression (making a protein in the cells of a different organism), and the creation of mutants.
Tomoo Sawabe, Professor
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The Marine Microbiology Lab aims to understand how microorganisms living in marine environments live (their physiology and ecology) and to carry out applied research that makes use of their characteristics. The lab works on applying marine microorganisms to the production of clean energy and the degradation of plastics. The lab also investigates the physiology, ecology, and diversity of microorganisms living in a variety of marine environments, and searches for microorganisms that reduce nitrous oxide, a greenhouse gas.
Hisae Kasai, Professor
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Professor Hisae Kasai's lab studies diseases of fish and shellfish and the safety of seafood from a microbiological perspective. In the seed production of fish and shellfish (hatchery rearing of juveniles), diseases caused by protozoa, fungi, bacteria, viruses, and other agents occur, and they greatly affect the results of later stocking and aquaculture. The lab carries out basic research that investigates how these diseases arise, and applied research that uses that knowledge to control the diseases. As a Reference Laboratory of the World Organisation for Animal Health (OIE) for viral diseases of salmonids, the lab also works on developing diagnostic methods and disease control measures.
Takeshi Yokoyama, Associate Professor
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Associate Professor Takeshi Yokoyama uses cryo-electron microscopy to determine the structures of biomolecules derived from marine organisms. Cryo-electron microscopy is a method in which biomolecules are rapidly frozen, trapped in a thin film of glass-like ice, and observed directly with a transmission electron microscope. The lab focuses on ribosome complexes and works on the structural analysis of a variety of biomacromolecular complexes. Samples are prepared in the lab, data are collected at cryo-electron microscopy facilities across Japan, and structural analysis and biochemical functional analysis are then carried out in the lab.
Hiroyuki Tanaka, Assistant Professor
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Assistant Professor Hiroyuki Tanaka studies proteins that function inside the cells of aquatic animals, aiming to clarify the mechanisms of biological phenomena and functions at the molecular level. Marine organisms have evolved their body forms and ecology to live in environments very different from those on land, such as low temperatures, high water pressure, and high salinity. Muscle, the organ of movement, also has unique features, and recently the lab has been focusing on the muscle proteins of cnidarians, represented by jellyfish.
Masaki Fujita, Associate Professor
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The Bioorganic Chemistry Lab studies compounds made by marine organisms and microbes from the perspective of organic chemistry. A wide variety of compounds, some of which are candidates for drugs, have been found in marine organisms, and many of them are made by symbiotic bacteria. The lab aims to find the genes needed to make these compounds and produce them biotechnologically, making use of marine resources that have not yet been utilized. The lab also investigates how organisms influence one another through chemical substances, in connection with red tides and cyanobacterial blooms (aoko).
Yasuhiro Ando, Associate Professor
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The Ando Lab studies the structure and composition of lipids in marine organisms. Lipids are substances derived from living organisms that dissolve poorly in water and dissolve well in oil. The lipids of aquatic organisms contain far more types of compounds than those of terrestrial animals and plants, and measuring their structures and amounts is not easy. The lab carefully analyzes lipid components in a wide range of fish, from familiar marine fish to wild Pacific bluefin tuna and rarely distributed species.
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