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107 labs · 0 student voices
Faculties at Kyushu University ›

Shozo Jinno, Professor
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The Neuroanatomy Lab studies how the brain operates, starting from the construction of neural circuits in the hippocampus, the center of memory and emotion. In addition to basic research on hippocampal neurons and glia, the lab studies psychiatric and neurological disorders using model mice for depression, drug addiction, schizophrenia, and other conditions. Centered on an image analysis system it developed in-house, the lab combines experimental techniques such as behavioral pharmacology, molecular biology, and chemogenetics. On the lab's website, it is presented under the name "Jinno Lab."

Chikara Meno, Professor
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The Developmental and Regenerative Medicine Lab uses mice to study how a complex individual is built from a single fertilized egg. After the embryo implants in the uterus, the body axes (anterior–posterior, dorsal–ventral, and left–right) are established, and the mesoderm moves anteriorly to form the precursor of the heart. The lab aims to clarify the molecular mechanisms that control these early developmental events through genetic analysis, imaging, and other approaches. Disruptions in early developmental events are also closely linked to infertility and congenital anomalies in humans.

Takashi Ito, Professor
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The Medical Chemistry Lab develops its own strategies from the standpoint of genome science and conducts research aimed at contributing to the understanding of living systems. With comprehensiveness and quantitative measurement as its keywords, the lab advances its research on the foundation of developing original technologies. Using budding yeast, the lab investigates gene expression and protein-protein interactions, and it also works on technologies for examining DNA methylation status across the entire genome. The lab wants to be a place that trains researchers with both comprehensive measurement and data analysis skills, and it welcomes students of any background.

Junichi Ikenouchi, Professor
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The Biochemistry Lab studies the structure and function of the plasma membrane of epithelial cells, with a focus on lipids. Textbook diagrams draw the plasma membrane as two gray lines, but in reality thousands of different lipid molecules are present. Starting from the question of why cells make and use so many kinds of lipids, the lab investigates cell adhesion and polarity formation in epithelial cells. The lab also studies how lipids relate to diseases caused by epithelial cell abnormalities, such as cancer and fibrosis.

Takashi Miura, Professor
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The Systematic Anatomy Lab studies how the shapes of organisms' bodies are formed, combining developmental biology and applied mathematics. Focusing on spontaneous pattern formation, in which an ordered form arises from a state with nothing in it, the lab has elucidated the principles of the mechanism using reaction-diffusion systems, a mathematical tool. The lab aims to connect the elucidation of the principles of shape formation to elucidating the mechanisms by which congenital anomalies form and to building tissue structures in regenerative medicine. The lab welcomes motivated people from a variety of backgrounds.

Takeshi Imai, Professor (Senior Chief Professor)
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The Disease Information Research Division (Imai Lab) studies how neural circuits in the brain develop and how they function. The lab investigates neural circuits from three angles (functional dynamics, structural basis of circuits, and developmental mechanisms), aiming to clarify the principles by which the brain is built and the mechanisms by which its functions arise. Using the mouse olfactory system and cerebral cortex as models, the lab studies neural activity with two-photon microscopy. It also independently develops tools for reading out the connectome with light microscopy, such as tissue clearing methods. In undergraduate education, the lab is in charge of physiology, and on the lab's website it is introduced as the "Imai Lab."

Keiji Kuba, Professor
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The Kuba Lab in the Pharmacology Division studies the molecular mechanisms of disease and previously unknown operating principles of life, using model animals and cells. The lab focuses on the interaction between two distinct mechanisms: RNA regulation and signal transduction. The diseases it targets are mainly heart failure, acute lung injury, and malignant tumors, and the lab plans to also tackle problems in other areas such as rare diseases. Its achievements so far include elucidating how the RNA regulator CCR4-NOT controls cardiac function, and developing an ACE2 convergent evolution enzyme to prevent severe COVID-19.

Hideaki Morishita, Professor
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The Morishita Lab in the Biological Function Division studies the molecular mechanisms and physiological significance of dramatic cellular phenomena that occur in the living body, as well as related diseases. In the lens, for example, cells destroy their nuclei and mitochondria all at once and are reborn as transparent tissue. Beyond intracellular degradation, the lab is widening its scope to cell fusion, terminal differentiation, and aging. It uses model organisms such as zebrafish and mice, combined with technologies such as omics.

Tomotake Kanki, Professor
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The Cell Physiology Lab (Kanki Lab) studies mitophagy, the mechanism by which mitochondria are degraded inside cells. Mitochondria are organelles that convert nutrients obtained from food into ATP, an energy form that cells can readily use. Mitophagy is a phenomenon in which autophagy, the process by which cells break down their own components, selectively degrades mitochondria. Using a wide range of species, from yeast to cultured mammalian cells and mice, the lab investigates everything from molecular mechanisms to physiological significance.

Kazunori Nakagawa, Lecturer
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The Pathology and Pathophysiology Lab investigates how vascular diseases arise, using tissue observation and molecular analysis. Focusing on atherosclerosis, the lab studies the process of vascular remodeling, in which blood vessels are pathologically restructured. In giant cell arteritis, an inflammatory disease of the blood vessels, the lab is working to clarify the significance of amyloid deposition. The Assistant Professor also teaches pathology lectures and practical courses for the Department of Medicine and the Department of Life Sciences.
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