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Systematic Anatomy Lab
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A lab that explores how organisms form their body shapes using mathematics and experiments.
AboutAbout the lab
Approaching body shape formation through mathematics and experiments
The Systematic Anatomy Lab studies how the shapes of organisms' bodies are formed, combining developmental biology and applied mathematics.
Focusing on spontaneous pattern formation, in which an ordered form arises from a state with nothing in it, the lab has elucidated the principles of the mechanism using reaction-diffusion systems, a mathematical tool.
The lab aims to connect the elucidation of the principles of shape formation to elucidating the mechanisms by which congenital anomalies form and to building tissue structures in regenerative medicine.
The lab welcomes motivated people from a variety of backgrounds.
Key terms
- Developmental biology
- The field that studies how the shape of the body comes to be formed
- Spontaneous pattern formation
- The phenomenon in which a periodic structure forms spontaneously from a distribution that originally appears uniform
- Reaction-diffusion system
- A tool in applied mathematics used to study pattern formation
NewsLab news
Paper on a 3D shaping method using shrinking sheets published in Journal of the Royal Society Interface
Study on waves of spermatogenesis published in Mathematical Biosciences
Study on human retinal vascular patterns published in Translational Vision Science and Technology
Study on lesion shapes in keratitis published in Bulletin of Mathematical Biology
Study on peristaltic movement of the esophagus published in Royal Society Open Science
ResearchResearch themes
Long lists of gene names have been compiled, but the principle of why shapes form is still not understood. This lab combines experimental methods of developmental biology with tools of applied mathematics, and aims to elucidate the mechanisms by which organisms form their shapes.
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MembersFaculty
- ProfessorTakashi Miura
- Associate ProfessorYuki Sato
- Assistant ProfessorKei Sugihara
- Assistant ProfessorKeisuke Matsuda
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Giant Puffer fish skin pattern” Chiswick Chap / CC BY-SA 3.0 (cropped)
- Mathematical modeling of pattern formation in mammalian embryos: “Leopard spots” Keven Law / CC BY-SA 2.0 (cropped)
- Related lab (マルチオミクス解析): “30nm Chromatin Structures” Zephyris at English Wikipedia / CC BY-SA 3.0 (cropped)
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- Related lab (ウイルス学): “Novel Coronavirus SARS-CoV-2” NIAID-RML (https://www.niaid.nih.gov/ & https://www.niaid.nih.gov/about/rocky-mountain-laboratories) / CC BY 2.0 (cropped)
- Related lab (生体機能学): “Eukayotic Cell (430x maginification)” Jlipuma1 / CC BY 4.0 (cropped)
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