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Pharmaceutical Design Lab
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The lab works on delivering new types of drugs, such as cells and nucleic acids, to targeted sites in the body.
AboutAbout the lab
The right amount, to the right place, at the right time.
The drugs administered for treatment come in many forms (modalities), including small-molecule compounds, proteins, nucleic acids and genes, and cells. To be effective in the body, a drug must reach the right place at the right time in the right amount, and the mechanism that controls this precisely is called a drug delivery system (DDS).
The Pharmaceutical Design Lab focuses on biopharmaceuticals and aims to establish new DDS strategies, along with methods to evaluate how these drugs behave inside the body.
Key terms
- Drug delivery system
- A mechanism that delivers a drug to the place where it is needed, at the time it is needed, and in only the amount needed.
- Modality
- The type or form of a drug, such as small molecules, antibodies, nucleic acids, and cells.
- Pharmacokinetics
- Where a drug that has entered the body goes, how it changes, and how it is eliminated.
- Extracellular vesicles
- Small particles that cells release outside themselves. They enclose substances and carry them to other cells.
ResearchResearch themes
The method for evaluating pharmacokinetics differs for each drug modality, so for new modalities such as biopharmaceuticals, the evaluation methods themselves must be established first.
*Illustrative imageAnalysis and control of the pharmacokinetics of biopharmaceuticals
The lab studies how to analyze and control the pharmacokinetics of biopharmaceuticals such as cells, extracellular vesicles, nucleic acids, and antibodies.
*Illustrative imageControlling cell function for cell therapy
The lab studies how to control cell function so that cells, used as therapeutic agents, can be delivered to the sites in the body that need treatment.
MembersFaculty
- ProfessorYuriko Higuchi
- Associate ProfessorYuki Takahashi
- Assistant ProfessorChengyuan Zhu
- Assistant ProfessorErika Yamashita
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Nanocapsule” GirlBossBME23 / CC BY-SA 4.0 (cropped)
- Analysis and control of the pharmacokinetics of biopharmaceuticals: “Antibody-drug conjugate” Bioconjugator / CC BY-SA 4.0 (cropped)
- Controlling cell function for cell therapy: “Dendritic cell therapy not annotated” Simon Caulton / CC BY-SA 3.0 (cropped)
- Related lab (Clinical Pharmacy Education Lab): “Kommissionierroboter in der Apotheke der Universitätsklinik Münster” UKM Elisabeth Deiters-Keul / CC BY-SA 3.0 (cropped)
- Related lab (Pharmaceutical Synthetic Chemistry Lab): “Verrerie-p1030896” Rama / CC BY-SA 2.0 fr (cropped)
- Related lab (Mathematical Therapeutics Lab): “Iodine pills” Mx. Granger / CC0 (cropped)
- Related lab (Systems Biology Lab): “Circadian rhythm labeled” National Institute of General Medical Sciences / Public domain (cropped)
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