LAB LOGA page on LabLog, a review site (not the lab's official page)
Pharmaceutical Molecular Chemistry Lab
Machine-translated · View original
An organic chemistry lab that uses the power of catalysts to remake drug molecules only at targeted positions.
AboutAbout the lab
Chemistry for creating and making medicines.
Organic chemistry is the discipline of understanding the properties, structures, and reactivity of organic molecules, manipulating them at will, and producing new molecules with unprecedented functions.
Building on discoveries of new phenomena in organic chemistry, the Pharmaceutical Molecular Chemistry Lab contributes to drug discovery science by developing new technologies for both discovering and manufacturing drugs and by elucidating biological phenomena.
Pharmaceuticals are expanding to diverse medium-sized and large molecules such as antibodies, peptides, and nucleic acids, and the lab develops its own methods to synthesize complex, large molecules efficiently and in an environmentally conscious way.
Key terms
- Deuterium
- Heavy hydrogen, which has one more neutron than ordinary hydrogen
- Catalyst
- A substance that speeds up or directs a chemical reaction without being changed itself
- Peptide
- A molecule made of a few to several dozen amino acids linked together
- Computational chemistry
- Chemistry that uses computers to calculate and predict the properties and reactions of molecules
ResearchResearch themes
In large molecules, controlling where a reaction takes place becomes difficult, so the lab conducts research through both experiments and computation, using computational chemistry and data science as tools.
*Illustrative imageOpening up molecular functions through deuteration
The lab studies the catalytic replacement of specific hydrogens with deuterium in a single step, and has found that iridium catalysts can easily deuterate pharmaceuticals in heavy water.
Remodeling peptides at pinpoint positions
The lab has developed methods that convert finished peptides into a variety of molecules in a single step. It is now developing catalysts that react peptides in a sequence-selective manner.
MembersFaculty
- Associate ProfessorHiroshi Naka
- LecturerTakeshi Nanjo
VoicesStudent voices
Compiled from answers by students who were in the lab. Ratings and reviews reflect individual students' experiences, not the lab's official views.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
On a 4-point scale, ● marks where students' answers fall
Who is this lab for?
What's great about this lab?
What did you learn after joining?
What's the vibe, and what is the professor like?
Where do graduates go?
RelatedLabs similar to Pharmaceutical Molecular Chemistry Lab
Pharmaceutical Synthetic Chemistry LabFaculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of PharmacyDesign and development of artificial molecules that exhibit …
Biofunctional Chemistry LabFaculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of PharmacyCreation of bioactive proteins regulating cell function and …
Pharmaceutical Design LabFaculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of PharmacyDesign and evaluation of drug delivery systems for biopharma…
Virus Control LabFaculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of PharmacyStudies on viral cell entry mechanisms / Studies on mechanis…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
For images provided to us or used with permission, the source is listed on each line. Wikimedia Commons images are illustrative and were not taken at the lab (they are cropped). Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Laboratory experiment room” 薬品分子化学研究室 / 研究室からの
提供 (cropped) - Opening up molecular functions through deuteration: “Deuterium-glow” en:User:Jurii (Transfered by Lanthanum-138/Original uploaded by Lanthanum-138) / CC BY 3.0 (cropped)
- Remodeling peptides at pinpoint positions: “Structure of a chlorinated peptide” 薬品分子化学研究室 / 研究室からの
提供 - Related lab (Pharmaceutical Synthetic Chemistry Lab): “Verrerie-p1030896” Rama / CC BY-SA 2.0 fr (cropped)
- Related lab (Biofunctional Chemistry Lab): “Zinc finger rendered” Thomas Splettstoesser (www.scistyle.com) / CC BY-SA 4.0 (cropped)
- Related lab (Pharmaceutical Design Lab): “Nanocapsule” GirlBossBME23 / CC BY-SA 4.0 (cropped)
- Related lab (Virus Control Lab): “Virus Particle Icon (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.