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Morphogenesis and Basic Medical Science (Pathology) Lab
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A pathology lab that captures the human form before birth in 3D to uncover how development works.

AboutAbout the lab
The world every person passes through before birth.
Humans are born 38 weeks after fertilization. The embryonic period, from 3 to 9 weeks after fertilization, is the critical stage when organs are formed. Developmental abnormalities are especially likely to occur during this period, which makes it important for basic research on congenital anomalies.
The Morphogenesis and Basic Medical Science Lab (Pathology Lab) studies the embryonic period and the early fetal period. It aims to understand accurate, normal human development and to uncover how congenital diseases arise.
Its ultimate goal is to clarify the universal world that all of humanity passes through before birth.
Key terms
- Embryonic period
- The period from about 3 to 9 weeks after fertilization, when the body's organs are formed
- Kyoto Collection
- A large collection of human embryo and fetus specimens held by Kyoto University
- MR microscopy
- A device that uses the principles of MRI to produce detailed images of the inside of small specimens
- Congenital anomalies
- Abnormalities in the form or function of the body that are present from birth
ResearchResearch themes
The lab images human embryos and fetuses held in the Kyoto Collection using the latest methods, such as MR microscopy and phase-contrast X-ray CT, to obtain 3D data and approach human development.
*Illustrative imageHuman Development Seen Through 3D Data
3D data can represent form accurately, allows many specimens to be handled efficiently by computer, and can be analyzed numerically. These features make possible what classical human embryology could not do.
*Illustrative imageOrganogenesis in the Embryonic and Fetal Periods
The lab analyzes how organs throughout the body are formed: the bronchi, brain, and kidneys in the embryonic period, and the brain, pelvis, heart, auditory ossicles, bony labyrinth, and femur in the fetal period.
*Illustrative imageDevelopment of the Heart and Vessels
The lab studies how the heart and vascular system are formed, aiming to understand how congenital morphological abnormalities arise.
MembersFaculty
- ProfessorTetsuya Takakuwa
- Assistant ProfessorToru Kanahashi
- Assistant ProfessorSena Fujii
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images.
- Top image: “Development of the notochord in a stage 8 (17–19 days) human embryo” de Bree K, de Bakker BS, Oostra R-J / CC BY 4.0 (cropped)
- Human Development Seen Through 3D Data: “Overview of the developing notochord in relation to the fusion of the dorsal aortae human embryo” de Bree K, de Bakker BS, Oostra R-J / CC BY 4.0 (cropped)
- Organogenesis in the Embryonic and Fetal Periods: “Schematic dorsal overview of the developing notochord and the fusion of the paired dorsal aortae in humans” de Bree K, de Bakker BS, Oostra R-J / CC BY 4.0 (cropped)
- Development of the Heart and Vessels: “2037 Embryonic Development of Heart” OpenStax College / CC BY 3.0 (cropped)
- Related lab (Developmental Neurobiology Lab): “The developing cerebral cortex” Shyam K Akula , David Exposito-Alonso , Christopher A Walsh / CC BY 4.0 (cropped)
- Related lab (Biomedical Data Science Lab): “Principles of machine learning” Langs, G., Röhrich, S., Hofmanninger, J. et al. / CC BY 4.0 (cropped)
- Related lab (Clinical Cognitive Neuroscience Lab): “Motor imagery” User:Decety / Public domain (cropped)
- Related lab (Biological Structure Lab (formerly Developmental Anatomy and Developmental Neuroscience Lab)): “Staging Human Gastrulation” Richard C.V. Tyser, Shankar Srinivas / CC BY 4.0 (cropped)
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