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Biological Structure Lab (formerly Developmental Anatomy and Developmental Neuroscience Lab)
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An anatomy lab that explores the mechanisms of congenital anomalies using a collection of human embryos.

AboutAbout the lab
How do congenital anomalies arise?
About 3% of newborns have a congenital anomaly, but the causes and mechanisms of onset have been clarified for only some of them.
Biological Structure brings together knowledge from basic medicine, clinical medicine, and epidemiology to study congenital anomalies.
Prof. Yamada also serves as a professor at the Congenital Anomaly Specimen Analysis Center affiliated with the Faculty of Medicine, and conducts research using the center's human embryo collection.
Key terms
- Congenital anomaly
- An abnormality in the form or function of the body that is present from birth
- Human embryo
- A human in the early stage of development, up to about 8 weeks after fertilization
- Internal disability
- Impairment of the function of internal organs such as the heart, lungs, and kidneys
ResearchResearch themes
Drawing on each faculty member's expertise, the lab studies topics ranging from how congenital anomalies develop to medical English education and rehabilitation.
*Illustrative imageThe Development of Congenital Anomalies Seen in Human Embryos
Centered on morphological studies using a large collection of human embryos, the lab investigates the early pathogenesis of congenital anomalies. It also works to identify causes using genetic epidemiological methods and studies developmental mechanisms through experimental research.
*Illustrative imageEnglish Communication for Healthcare Professionals
The lab conducts research on English communication skills training and intercultural competence for healthcare professionals in Japan. It also develops online teaching materials and self-assessment tools.
*Illustrative imageMovement, Sensation, and Rehabilitation
The lab studies movement and sensation, and rehabilitation using animal models of disease. It also researches rehabilitation for internal disabilities.
MembersFaculty
- ProfessorShigehito Yamada
- Associate ProfessorMihoko Hayashi
- Assistant ProfessorKazuhiro Hayashi
VoicesStudent voices
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Report an errorAbout the images
For images provided to us or used with permission, the source is listed on each line. Wikimedia Commons images are illustrative and were not taken at the lab (they are cropped). Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Staging Human Gastrulation” Richard C.V. Tyser, Shankar Srinivas / CC BY 4.0 (cropped)
- The Development of Congenital Anomalies Seen in Human Embryos: “Yolk sac human” Ross, C., Boroviak, T.E. / CC BY 4.0 (cropped)
- English Communication for Healthcare Professionals: “Nurse attending to a patient” Bruno ashimwe winks / CC BY-SA 4.0 (cropped)
- Movement, Sensation, and Rehabilitation: “Physical Therapy Teaching Lab at CU Anschutz (October 2025)” Mikepascoe / CC0 (cropped)
- Related lab (脳機能リハビリテーション学): “Occupational therapist helping a client create a job resume to send out to future employers” Mangionekd / CC BY-SA 4.0 (cropped)
- Related lab (生体物理リハビリテーション研究室): “Physiotherapy therapy and occupational therapy” Ashashyou / CC BY-SA 3.0 (cropped)
- Related lab (ニューロリハビリテーション研究室): “Neurorehabilitation Class” ニューロリハビリテーション研究室 / 研究室からの
提供 (cropped) - Related lab (イノベーティブ リハビリテーション科学研究室): “Thirty-five rowers on a long racing pirogue in Laos” Basile Morin / CC BY-SA 4.0 (cropped)
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