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Pathophysiological Biomedicine Lab
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The lab uses its own original technologies to decipher how the human genome functions in the body.
AboutAbout the lab
Understanding disease and creating medicine from how the human genome works
The Pathophysiological Biomedicine Lab aims to create new ways of understanding disease and new medical care from the information in the genome, the blueprint of the human body.
By combining cutting-edge measurement technologies, informatics, and classical biochemistry, the lab develops original genome analysis technologies and investigates the mechanisms of disease at the levels of genes, molecules, and cells.
In collaboration with hospitals and research institutes, the lab builds large-scale data platforms and conducts research focused on the new genes discovered through them.
Key terms
- Genome
- The entire set of genetic information of an organism. In humans, it consists of about 3.1 billion base pairs of DNA.
- RNA
- A molecule made by copying information from DNA. It is produced when a gene is active.
- Single-cell analysis
- A method that separates cells one by one and examines how genes work in each of them.
NewsLab news
Prof. Murakawa received the Young Investigator Award of the 2nd Kobe Award
Research results published in Science
ResearchResearch themes
Little is known about how an individual's genetic information functions in the body and determines how disease arises. By integrating biochemistry, molecular biology, information science, primatology, and medicine, the lab studies the human genome, which makes us human.
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MembersFaculty
Members of the Pathophysiological Biomedicine Lab (Murakawa Group) consist of faculty, doctoral students, project researchers, undergraduate students, RIKEN researchers and technical staff, and secretaries.
- ProfessorYasuhiro Murakawa
- Project LecturerKohei Hamanaka
- LecturerIzumi Yanatori
- Assistant ProfessorKazuhiro Takeuchi
- Program-Specific Assistant ProfessorShruti Bhagat
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Oxford Nanopore Technologies Mk1c” Rojoxiii / CC0 (cropped)
- Precisely measuring how the human genome works, cell by cell: “MinION portable sequencer” Mongan A.E. / CC BY 4.0 (cropped)
- Related lab (Laboratory Animal Science Lab): “Eppendorf pipet” Jucember / CC BY-SA 3.0 (cropped)
- Related lab (Cancer Immune Multicellular System Regulation Lab): “Dendritic Cell (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (Disease Genome Epidemiology and Genome Informatics Lab (Center for Genomic Medicine)): “Hokkoku Kaido, Nagahama 05” Sachi0myk / CC BY-SA 4.0 (cropped)
- Related lab (Medical Chemistry Lab): “Macrophage by NIAID” NIAID / CC BY 2.0 (cropped)
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