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Uchiumi Lab
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A biochemistry and molecular biology lab exploring the mechanisms that regulate gene expression.
AboutAbout the lab
Unraveling the regulation of gene expression.
The Uchiumi Lab studies the mechanisms that determine how strongly genes are expressed, among the genetic information written in DNA.
The lab investigates how the expression of genes involved in carcinogenesis, metabolism, and aging, as well as interferon-stimulated genes, is regulated.
By identifying genes that play important roles, the lab aims to develop new gene-based therapies for cancer and immune diseases.
The lab is introduced as a lab of the Department of Life Sciences and Drug Discovery in the Faculty of Pharmaceutical Sciences at the undergraduate level, and of the Department of Pharmaceutical Sciences in the Graduate School of Pharmaceutical Sciences at the graduate level.
Key terms
- Gene expression
- The actual use of a gene's information. How much it is used is also determined by the code in DNA.
- Interferon-stimulated gene
- A gene whose expression changes in response to a substance called interferon.
ResearchResearch themes
An organism's genetic information is stored as a code in DNA, which determines not only the structure of proteins but also how strongly genes are expressed. The lab conducts basic research to clarify how gene expression is regulated, with the aim of developing new treatments for cancer and immune diseases.
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MembersFaculty
- ProfessorFumiaki Uchiumi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “DNA Double Helix by NHGRI” National Human Genome Research Institute / Public domain (cropped)
- Mechanisms Regulating Gene Expression: “Transcription and Translation” Christinelmiller / CC BY-SA 4.0 (cropped)
- Related lab (原田研究室): “T Lymphocyte ( )” NIAID / CC BY 2.0 (cropped)
- Related lab (秋本研究室): “BS-Fig1” Goodwin G. Jinesh / CC BY-SA 4.0 (cropped)
- Related lab (横山研究室): “CSIRO ScienceImage 1304 Protein crystals” division, CSIRO / CC BY 3.0 (cropped)
- Related lab (早田研究室): “Mouse embryonic salivary gland growing in vitro” Irebustini / CC BY 4.0 (cropped)
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