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Sekine Lab
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The lab uses high-resolution imaging to decipher how living organisms form their shapes.
AboutAbout the lab
The rhythm and blueprint of life, created by form.
The Sekine Lab studies how the shapes of living organisms' bodies are formed.
Using high-resolution imaging, the lab captures the shapes of tissues, cells, and molecular assemblies.
It investigates how the heartbeat rhythm is generated and how it supports the construction of whole-body function.
The lab aims to connect the mechanisms it uncovers to the design of living systems.
Key terms
- High-resolution imaging
- A technique that uses microscopes and similar instruments to capture images in which fine structures of cells and molecules can be distinguished.
- Tubular tissue
- A body tissue shaped like a tube with a hollow interior, such as blood vessels and the trachea.
- Self-assembly
- The formation of an ordered structure through interactions among components, without a shape being imposed from outside.
ResearchResearch themes
The lab uses high-resolution imaging to capture the shapes of tissues, cells, and molecular assemblies. It investigates how the heartbeat rhythm is generated and how it supports the construction of whole-body function, and links these findings to the design of living systems.
*Illustrative imageImaging to capture form
The lab captures the shapes formed by tissues, cells, and molecular assemblies with high-resolution imaging. It analyzes the acquired images to decipher the process by which these shapes emerge.
*Illustrative imageSelf-assembly of tubular tissues
In tubular tissues such as the Drosophila trachea, the lab studies the mechanism by which small clusters of actin align on their own and give rise to periodic structures.
*Illustrative imageThe rhythm of the heartbeat
The lab investigates how the rhythm of the heartbeat is generated and how it supports the assembly of whole-body function.
MembersFaculty
- Associate ProfessorSayaka Sekine
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Multicolor fluorescence image of living HeLa cells” 8x57is / CC BY-SA 4.0 (cropped)
- Imaging to capture form: “Development of the retina” IchaJaroslav / CC BY-SA 4.0 (cropped)
- Self-assembly of tubular tissues: “Drosophila melanogaster - side (aka)” André Karwath aka Aka / CC BY-SA 2.5 (cropped)
- The rhythm of the heartbeat: “Muscle Tissue Cardiac Muscle ( )” Berkshire Community College Bioscience Image Library / CC0 (cropped)
- Related lab (加納研究室): “Osteosarcoma cells stained for actin, microtubules, and nuclei” Howard Vindin / CC BY 4.0 (cropped)
- Related lab (蒲池研究室): “Carboxyhemoglobin from 1AJ9” Rifleman 82 / CC BY-SA 3.0 (cropped)
- Related lab (神谷研究室): “Fluorescence rainbow” Maxim Bilovitskiy / CC BY-SA 4.0 (cropped)
- Related lab (北口研究室): “Crystal Jelly ("Aequorea Victoria"), Monterey Bay Aquarium, Monterey, California, USA” Jim G from Silicon Valley, CA, USA / CC BY 2.0 (cropped)
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