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Radiation Oncology Lab
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The lab treats cancer with radiation such as proton beams and researches how to do so.
AboutAbout the lab
Researching cancer treatment with proton therapy and BNCT.
The Radiation Oncology Lab works on clinical care and research in radiation therapy for cancer at the Proton Therapy Center, which is part of the university hospital.
The University of Tsukuba began full-scale research on proton therapy in 1983, giving it the longest history of any institution in Japan.
Proton therapy can focus radiation precisely on the cancer lesion, so it has little effect on the surrounding normal cells and is characterized by milder side effects.
In addition, the Proton Medical Research Center makes research and development of boron neutron capture therapy (BNCT), a new cancer treatment, its other main pillar.
Key terms
- Proton therapy
- Radiation therapy that can irradiate a cancer lesion with pinpoint accuracy, with little effect on the surrounding normal cells and milder side effects.
- BNCT
- Short for boron neutron capture therapy. A new cancer treatment expected to be effective for intractable and recurrent cancers.
NewsLab news
Professor Hideyuki Sakurai was selected as Best Teacher in the fiscal 2025 (Reiwa 7) M6 student vote
Faculty members, graduate students, and nursing staff received the Outstanding Presentation Award at the 22nd Ibaraki Radiation Oncology Study Group meeting
Professor Hideyuki Sakurai was selected as Best Teacher for CC Phase II in fiscal 2025 (Reiwa 7)
A hospital lecturer received the Best Award at the 27th Annual Meeting of the Brachytherapy Subcommittee
A physician received the Hospital Director's Award for Outstanding Resident Paper (fiscal 2024) at University of Tsukuba Hospital
ResearchResearch themes
The Proton Medical Research Center makes use of its treatment facilities for both proton therapy and boron neutron capture therapy (BNCT) to develop equipment and software, study drugs, and research new treatment methods. In addition to basic research, it conducts clinical research aimed at more precise treatment, in cooperation with the staff of the Proton Therapy Center, which provides the treatment.
*Illustrative imagePrecise Targeting Techniques and AI
Physicians, medical physicists, and researchers have worked together to develop techniques for targeting cancer accurately and quickly. They are now combining these with AI to develop even more accurate irradiation techniques.
*Illustrative imageResearch and Development of BNCT
Boron neutron capture therapy is expected to be a treatment for intractable and recurrent cancers. The lab has developed an accelerator-based treatment device capable of generating high-intensity neutrons, and is conducting a clinical trial with this device for newly diagnosed malignant brain tumors.
*Illustrative imageMulticenter Clinical Studies with JCOG
Together with the Japan Clinical Oncology Group (JCOG), the lab is carrying out multicenter interventional clinical studies. These include a comparison of proton therapy and surgical resection for resectable hepatocellular carcinoma, as well as trials for cancers of the lung, esophagus, head and neck, and uterine cervix.
MembersFaculty
- ProfessorHideyuki Sakurai
- ProfessorTomonori Isobe
- Associate ProfessorKei Nakai
- Associate ProfessorMasashi Mizumoto
- LecturerHaruko Numajiri
- LecturerTakashi Saitoh
- Hospital LecturerTakashi Iizumi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Maximar 100 X-Ray Unit Superficial Therapy” Pairko / CC BY-SA 4.0 (cropped)
- Precise Targeting Techniques and AI: “Radiation-oncology” Hope / CC BY-SA 3.0 (cropped)
- Research and Development of BNCT: “Boron neutron capture therapy (bnct) illustration” Pat Kenny (Illustrator) / Public domain (cropped)
- Multicenter Clinical Studies with JCOG: “Aust.-Synchrotron-Interior-Panorama” jjron / CC BY-SA 3.0 (cropped)
- Related lab (Radiation Biology Lab): “Nuclear reactor at TINT” Azitc / CC BY-SA 4.0 (cropped)
- Related lab (Otorhinolaryngology and Head and Neck Surgery Lab): “Hearing exam 140517-Z-ME883-008” Senior Airman Kellyann Novak / Public domain (cropped)
- Related lab (Radiation Health Risk Science Lab): “8th CES and 8th MDG maintain nuclear and radiation emergency response readiness (9330024)” U.S. Air Force photo by Senior Airman Karissa Dick / Public domain (cropped)
- Related lab (Medical Physics Lab): “Radiotherapie” Guy Lebègue / CC BY-SA 3.0 (cropped)
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